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Nasopharyngeal carcinoma MHC region deep sequencing identifies HLA and novel non-HLA TRIM31 and TRIM39 loci

Despite pronounced associations of major histocompatibility complex (MHC) regions with nasopharyngeal carcinoma (NPC), causal variants underlying NPC pathogenesis remain elusive. Our large-scale comprehensive MHC region deep sequencing study of 5689 Hong Kong Chinese identifies eight independent NPC...

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Detalles Bibliográficos
Autores principales: Ning, Lvwen, Ko, Josephine Mun-Yee, Yu, Valen Zhuoyou, Ng, Hoi Yan, Chan, Candy King-Chi, Tao, Lihua, Lam, Shiu-Yeung, Leong, Merrin Man-Long, Ngan, Roger Kai-Cheong, Kwong, Dora Lai-Wan, Lee, Anne Wing-Mui, Ng, Wai-Tong, Cheng, Ashley, Tung, Stewart, Lee, Victor Ho-Fun, Lam, Ka-On, Kwan, Chung-Kong, Li, Wing-Sum, Yau, Stephen, Bei, Jin-Xin, Lung, Maria Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733486/
https://www.ncbi.nlm.nih.gov/pubmed/33311639
http://dx.doi.org/10.1038/s42003-020-01487-y