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The energy savings-oxidative cost trade-off for migratory birds during endurance flight

Elite human and animal athletes must acquire the fuels necessary for extreme feats, but also contend with the oxidative damage associated with peak metabolic performance. Here, we show that a migratory bird with fuel stores composed of more omega-6 polyunsaturated fats (PUFA) expended 11% less energ...

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Autores principales: McWilliams, Scott, Pierce, Barbara, Wittenzellner, Andrea, Langlois, Lillie, Engel, Sophia, Speakman, John R, Fatica, Olivia, DeMoranville, Kristen, Goymann, Wolfgang, Trost, Lisa, Bryla, Amadeusz, Dzialo, Maciej, Sadowska, Edyta, Bauchinger, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733536/
https://www.ncbi.nlm.nih.gov/pubmed/33306947
http://dx.doi.org/10.7554/eLife.60626
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author McWilliams, Scott
Pierce, Barbara
Wittenzellner, Andrea
Langlois, Lillie
Engel, Sophia
Speakman, John R
Fatica, Olivia
DeMoranville, Kristen
Goymann, Wolfgang
Trost, Lisa
Bryla, Amadeusz
Dzialo, Maciej
Sadowska, Edyta
Bauchinger, Ulf
author_facet McWilliams, Scott
Pierce, Barbara
Wittenzellner, Andrea
Langlois, Lillie
Engel, Sophia
Speakman, John R
Fatica, Olivia
DeMoranville, Kristen
Goymann, Wolfgang
Trost, Lisa
Bryla, Amadeusz
Dzialo, Maciej
Sadowska, Edyta
Bauchinger, Ulf
author_sort McWilliams, Scott
collection PubMed
description Elite human and animal athletes must acquire the fuels necessary for extreme feats, but also contend with the oxidative damage associated with peak metabolic performance. Here, we show that a migratory bird with fuel stores composed of more omega-6 polyunsaturated fats (PUFA) expended 11% less energy during long-duration (6 hr) flights with no change in oxidative costs; however, this short-term energy savings came at the long-term cost of higher oxidative damage in the omega-6 PUFA-fed birds. Given that fatty acids are primary fuels, key signaling molecules, the building blocks of cell membranes, and that oxidative damage has long-term consequences for health and ageing, the energy savings-oxidative cost trade-off demonstrated here may be fundamentally important for a wide diversity of organisms on earth.
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spelling pubmed-77335362020-12-14 The energy savings-oxidative cost trade-off for migratory birds during endurance flight McWilliams, Scott Pierce, Barbara Wittenzellner, Andrea Langlois, Lillie Engel, Sophia Speakman, John R Fatica, Olivia DeMoranville, Kristen Goymann, Wolfgang Trost, Lisa Bryla, Amadeusz Dzialo, Maciej Sadowska, Edyta Bauchinger, Ulf eLife Biochemistry and Chemical Biology Elite human and animal athletes must acquire the fuels necessary for extreme feats, but also contend with the oxidative damage associated with peak metabolic performance. Here, we show that a migratory bird with fuel stores composed of more omega-6 polyunsaturated fats (PUFA) expended 11% less energy during long-duration (6 hr) flights with no change in oxidative costs; however, this short-term energy savings came at the long-term cost of higher oxidative damage in the omega-6 PUFA-fed birds. Given that fatty acids are primary fuels, key signaling molecules, the building blocks of cell membranes, and that oxidative damage has long-term consequences for health and ageing, the energy savings-oxidative cost trade-off demonstrated here may be fundamentally important for a wide diversity of organisms on earth. eLife Sciences Publications, Ltd 2020-12-11 /pmc/articles/PMC7733536/ /pubmed/33306947 http://dx.doi.org/10.7554/eLife.60626 Text en © 2020, McWilliams et al http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Biochemistry and Chemical Biology
McWilliams, Scott
Pierce, Barbara
Wittenzellner, Andrea
Langlois, Lillie
Engel, Sophia
Speakman, John R
Fatica, Olivia
DeMoranville, Kristen
Goymann, Wolfgang
Trost, Lisa
Bryla, Amadeusz
Dzialo, Maciej
Sadowska, Edyta
Bauchinger, Ulf
The energy savings-oxidative cost trade-off for migratory birds during endurance flight
title The energy savings-oxidative cost trade-off for migratory birds during endurance flight
title_full The energy savings-oxidative cost trade-off for migratory birds during endurance flight
title_fullStr The energy savings-oxidative cost trade-off for migratory birds during endurance flight
title_full_unstemmed The energy savings-oxidative cost trade-off for migratory birds during endurance flight
title_short The energy savings-oxidative cost trade-off for migratory birds during endurance flight
title_sort energy savings-oxidative cost trade-off for migratory birds during endurance flight
topic Biochemistry and Chemical Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733536/
https://www.ncbi.nlm.nih.gov/pubmed/33306947
http://dx.doi.org/10.7554/eLife.60626
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