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Delta-secretase triggers Alzheimer’s disease pathologies in wild-type hAPP/hMAPT double transgenic mice

Alzheimer’s disease (AD) is the most common neurodegenerative disease with multifactorial pathologies including Aβ containing senile plaques and neurofibrillary tangles (NFT) consisted of aggregated Tau. Most of the AD patients are sporadic and the familial mutation hereditary patients are composed...

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Detalles Bibliográficos
Autores principales:	Wu, Zhourui, Liu, Xia, Cheng, Liming, Ye, Keqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733592/ https://www.ncbi.nlm.nih.gov/pubmed/33311478 http://dx.doi.org/10.1038/s41419-020-03270-7

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