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Efficient inference, potential, and limitations of site-specific substitution models

Natural selection imposes a complex filter on which variants persist in a population resulting in evolutionary patterns that vary greatly along the genome. Some sites evolve close to neutrally, while others are highly conserved, allow only specific states, or only change in concert with other sites....

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Detalles Bibliográficos
Autores principales: Puller, Vadim, Sagulenko, Pavel, Neher, Richard A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733610/
https://www.ncbi.nlm.nih.gov/pubmed/33343922
http://dx.doi.org/10.1093/ve/veaa066