HIV-1 p24Gag adaptation to modern and archaic HLA-allele frequency differences in ethnic groups contributes to viral subtype diversification

Pathogen-driven selection and past interbreeding with archaic human lineages have resulted in differences in human leukocyte antigen (HLA)-allele frequencies between modern human populations. Whether or not this variation affects pathogen subtype diversification is unknown. Here we show a strong pos...

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Detalles Bibliográficos
Autores principales: Kist, Nicolaas C, Lambert, Ben, Campbell, Samuel, Katzourakis, Aris, Lunn, Daniel, Lemey, Philippe, Iversen, Astrid K N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733611/
https://www.ncbi.nlm.nih.gov/pubmed/33343925
http://dx.doi.org/10.1093/ve/veaa085

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