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Prevalence of epilepsy in Bangladesh: Results from a national household survey

OBJECTIVE: To determine the prevalence and types of epilepsy in Bangladesh. METHODS: We conducted a nationwide population‐based cross‐sectional survey among Bangladeshi population of all ages, except children under one month. We surveyed 9839 participants (urban, 4918; rural, 4920) recruited at thei...

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Autores principales: Mohammad, Quazi Deen, Saha, Narayan Chandra, Alam, Md Badrul, Hoque, Seikh Azimul, Islam, Ariful, Chowdhury, Rajib Nayan, Hussain, Mohammad Enayet, Chowdhury, Yamin Shahriar, Hossain, Sakhawat, Chowdhury, Mahmood Ahmed, Rahman, Matiur, Majumder, Bikash Kumar, Salam, Abdus, Sarker, Amitabh, Uddin, Md Kafil, Moniruzzaman, Mohammad, Hakim, Ferdous, Bhuiyan, Rijwan, Anwar, Nazneen, Zaman, Mohammad Mostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733657/
https://www.ncbi.nlm.nih.gov/pubmed/33336124
http://dx.doi.org/10.1002/epi4.12430
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author Mohammad, Quazi Deen
Saha, Narayan Chandra
Alam, Md Badrul
Hoque, Seikh Azimul
Islam, Ariful
Chowdhury, Rajib Nayan
Hussain, Mohammad Enayet
Chowdhury, Yamin Shahriar
Hossain, Sakhawat
Chowdhury, Mahmood Ahmed
Rahman, Matiur
Majumder, Bikash Kumar
Salam, Abdus
Sarker, Amitabh
Uddin, Md Kafil
Moniruzzaman, Mohammad
Hakim, Ferdous
Bhuiyan, Rijwan
Anwar, Nazneen
Zaman, Mohammad Mostafa
author_facet Mohammad, Quazi Deen
Saha, Narayan Chandra
Alam, Md Badrul
Hoque, Seikh Azimul
Islam, Ariful
Chowdhury, Rajib Nayan
Hussain, Mohammad Enayet
Chowdhury, Yamin Shahriar
Hossain, Sakhawat
Chowdhury, Mahmood Ahmed
Rahman, Matiur
Majumder, Bikash Kumar
Salam, Abdus
Sarker, Amitabh
Uddin, Md Kafil
Moniruzzaman, Mohammad
Hakim, Ferdous
Bhuiyan, Rijwan
Anwar, Nazneen
Zaman, Mohammad Mostafa
author_sort Mohammad, Quazi Deen
collection PubMed
description OBJECTIVE: To determine the prevalence and types of epilepsy in Bangladesh. METHODS: We conducted a nationwide population‐based cross‐sectional survey among Bangladeshi population of all ages, except children under one month. We surveyed 9839 participants (urban, 4918; rural, 4920) recruited at their households using multistage cluster sampling. Trained physicians with neurology background confirmed the diagnosis of suspected epilepsy cases identified by interviewer‐administered questionnaires. We reported the overall and sex, residence, and age groups‐specific prevalence of epilepsy per 1000 populations with 95% confidence interval. RESULTS: The national prevalence of epilepsy per 1000 was 8.4 (95% CI 5.6‐11.1), urban 8.0 (4.6‐11.4), and rural 8.5 (5.60‐11.5). The prevalence in adult males and females was 9.2 (5.7‐12.6) and 7.7 (3.6‐11.7), respectively. The prevalence in children aged <18 years (8.2, 3.4‐13.0 was similar to adults (8.5 (5.4‐11.4). Among all epilepsy cases, 65.1% had active epilepsy. Their (active epilepsy) prevalence was 5.8 (3.5‐8.1). Of them, 63.4% were not receiving treatment. Moreover, those who received allopathy treatment, 72.5% had low adherence leading to a high treatment gap. SIGNIFICANCE: Our findings out of this first‐ever national survey were similar to other Asian countries. However, the prevalence of active epilepsy and treatment gap were considerably higher. This study serves useful evidence for tailoring interventions aimed to reduce the burden of epilepsy—primarily through targeted community awareness program—and access to antiepileptic treatment in health facilities in Bangladesh.
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spelling pubmed-77336572020-12-16 Prevalence of epilepsy in Bangladesh: Results from a national household survey Mohammad, Quazi Deen Saha, Narayan Chandra Alam, Md Badrul Hoque, Seikh Azimul Islam, Ariful Chowdhury, Rajib Nayan Hussain, Mohammad Enayet Chowdhury, Yamin Shahriar Hossain, Sakhawat Chowdhury, Mahmood Ahmed Rahman, Matiur Majumder, Bikash Kumar Salam, Abdus Sarker, Amitabh Uddin, Md Kafil Moniruzzaman, Mohammad Hakim, Ferdous Bhuiyan, Rijwan Anwar, Nazneen Zaman, Mohammad Mostafa Epilepsia Open Full‐length Original Research OBJECTIVE: To determine the prevalence and types of epilepsy in Bangladesh. METHODS: We conducted a nationwide population‐based cross‐sectional survey among Bangladeshi population of all ages, except children under one month. We surveyed 9839 participants (urban, 4918; rural, 4920) recruited at their households using multistage cluster sampling. Trained physicians with neurology background confirmed the diagnosis of suspected epilepsy cases identified by interviewer‐administered questionnaires. We reported the overall and sex, residence, and age groups‐specific prevalence of epilepsy per 1000 populations with 95% confidence interval. RESULTS: The national prevalence of epilepsy per 1000 was 8.4 (95% CI 5.6‐11.1), urban 8.0 (4.6‐11.4), and rural 8.5 (5.60‐11.5). The prevalence in adult males and females was 9.2 (5.7‐12.6) and 7.7 (3.6‐11.7), respectively. The prevalence in children aged <18 years (8.2, 3.4‐13.0 was similar to adults (8.5 (5.4‐11.4). Among all epilepsy cases, 65.1% had active epilepsy. Their (active epilepsy) prevalence was 5.8 (3.5‐8.1). Of them, 63.4% were not receiving treatment. Moreover, those who received allopathy treatment, 72.5% had low adherence leading to a high treatment gap. SIGNIFICANCE: Our findings out of this first‐ever national survey were similar to other Asian countries. However, the prevalence of active epilepsy and treatment gap were considerably higher. This study serves useful evidence for tailoring interventions aimed to reduce the burden of epilepsy—primarily through targeted community awareness program—and access to antiepileptic treatment in health facilities in Bangladesh. John Wiley and Sons Inc. 2020-09-18 /pmc/articles/PMC7733657/ /pubmed/33336124 http://dx.doi.org/10.1002/epi4.12430 Text en © 2020 The Authors. Epilepsia Open published by Wiley Periodicals LLC on behalf of International League Against Epilepsy This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Full‐length Original Research
Mohammad, Quazi Deen
Saha, Narayan Chandra
Alam, Md Badrul
Hoque, Seikh Azimul
Islam, Ariful
Chowdhury, Rajib Nayan
Hussain, Mohammad Enayet
Chowdhury, Yamin Shahriar
Hossain, Sakhawat
Chowdhury, Mahmood Ahmed
Rahman, Matiur
Majumder, Bikash Kumar
Salam, Abdus
Sarker, Amitabh
Uddin, Md Kafil
Moniruzzaman, Mohammad
Hakim, Ferdous
Bhuiyan, Rijwan
Anwar, Nazneen
Zaman, Mohammad Mostafa
Prevalence of epilepsy in Bangladesh: Results from a national household survey
title Prevalence of epilepsy in Bangladesh: Results from a national household survey
title_full Prevalence of epilepsy in Bangladesh: Results from a national household survey
title_fullStr Prevalence of epilepsy in Bangladesh: Results from a national household survey
title_full_unstemmed Prevalence of epilepsy in Bangladesh: Results from a national household survey
title_short Prevalence of epilepsy in Bangladesh: Results from a national household survey
title_sort prevalence of epilepsy in bangladesh: results from a national household survey
topic Full‐length Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733657/
https://www.ncbi.nlm.nih.gov/pubmed/33336124
http://dx.doi.org/10.1002/epi4.12430
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