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Therapeutics—how to treat phase separation-associated diseases

Liquid–liquid phase separation has drawn attention as many neurodegeneration or cancer-associated proteins are able to form liquid membraneless compartments (condensates) by liquid–liquid phase separation. Furthermore, there is rapidly growing evidence that disease-associated mutation or post-transl...

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Detalles Bibliográficos
Autor principal: Wheeler, Richard John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733670/
https://www.ncbi.nlm.nih.gov/pubmed/32364240
http://dx.doi.org/10.1042/ETLS20190176

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