Identification of CD8(+) T cell epitopes through proteasome cleavage site predictions

BACKGROUND: We previously introduced PCPS (Proteasome Cleavage Prediction Server), a web-based tool to predict proteasome cleavage sites using n-grams. Here, we evaluated the ability of PCPS immunoproteasome cleavage model to discriminate CD8(+) T cell epitopes. RESULTS: We first assembled an epitop...

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Detalles Bibliográficos
Autores principales: Gomez-Perosanz, Marta, Ras-Carmona, Alvaro, Lafuente, Esther M., Reche, Pedro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733697/
https://www.ncbi.nlm.nih.gov/pubmed/33308150
http://dx.doi.org/10.1186/s12859-020-03782-1

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