Cargando…

Targeted photodynamic therapy selectively kills activated fibroblasts in experimental arthritis

OBJECTIVE: In RA, synovial fibroblasts become activated. These cells express fibroblast activation protein (FAP) and contribute to the pathogenesis by producing cytokines, chemokines and proteases. Selective depletion in inflamed joints could therefore constitute a viable treatment option. To this e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dorst, Daphne N, Rijpkema, Mark, Boss, Marti, Walgreen, Birgitte, Helsen, Monique M A, Bos, Desirée L, Brom, Maarten, Klein, Christian, Laverman, Peter, van der Kraan, Peter M, Gotthardt, Martin, Koenders, Marije I, Buitinga, Mijke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Basic and Translational Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733717/ https://www.ncbi.nlm.nih.gov/pubmed/32734285 http://dx.doi.org/10.1093/rheumatology/keaa295

Ejemplares similares

Photodynamic Therapy Targeting Macrophages Using IRDye700DX-Liposomes Decreases Experimental Arthritis Development
por: Dorst, Daphne N., et al.
Publicado: (2021)

Targeting of fibroblast activation protein in rheumatoid arthritis patients: imaging and ex vivo photodynamic therapy
por: Dorst, Daphne N, et al.
Publicado: (2021)

Fibroblast Activation Protein Targeted Photodynamic Therapy Selectively Kills Activated Skin Fibroblasts from Systemic Sclerosis Patients and Prevents Tissue Contraction
por: Dorst, Daphne N., et al.
Publicado: (2021)

Receptor-Targeted Photodynamic Therapy of Glucagon-Like Peptide 1 Receptor–Positive Lesions
por: Boss, Marti, et al.
Publicado: (2020)

Systemic overexpression of interleukin-22 induces the negative immune-regulator SOCS3 and potently reduces experimental arthritis in mice
por: Aarts, Joyce, et al.
Publicado: (2020)

PET-Based Human Dosimetry of (68)Ga-NODAGA-Exendin-4, a Tracer for β-Cell Imaging
por: Boss, Marti, et al.
Publicado: (2020)

Systemic Resolvin E1 (RvE1) Treatment Does Not Ameliorate the Severity of Collagen-Induced Arthritis (CIA) in Mice: A Randomized, Prospective, and Controlled Proof of Concept Study
por: de Molon, Rafael Scaf, et al.
Publicado: (2019)

Targeted Optical Imaging of the Glucagonlike Peptide 1 Receptor Using Exendin-4-IRDye 800CW
por: Boss, Marti, et al.
Publicado: (2020)

Exendin‐4 analogs in insulinoma theranostics
por: Jansen, Tom.J.P., et al.
Publicado: (2019)

Importance of beta cell mass for glycaemic control in people with type 1 diabetes
por: Jansen, Theodorus J. P., et al.
Publicado: (2022)

Local inhibition of TGF-β1 signaling improves Th17/Treg balance but not joint pathology during experimental arthritis
por: Aarts, Joyce, et al.
Publicado: (2022)

Methotrexate used in combination with aminolaevulinic acid for photodynamic killing of prostate cancer cells
por: Sinha, A K, et al.
Publicado: (2006)

Higher efficacy of anti-IL-6/IL-21 combination therapy compared to monotherapy in the induction phase of Th17-driven experimental arthritis
por: Roeleveld, Debbie M., et al.
Publicado: (2017)

Early pain in females is linked to late pathological features in murine experimental osteoarthritis
por: Valdrighi, Natália, et al.
Publicado: (2023)

Non-invasive in vivo determination of viable islet graft volume by (111)In-exendin-3
por: Eter, Wael A., et al.
Publicado: (2017)

CD64 as novel molecular imaging marker for the characterization of synovitis in rheumatoid arthritis
por: Theeuwes, Wessel F., et al.
Publicado: (2023)

Innate Immunity and Sex: Distinct Inflammatory Profiles Associated with Murine Pain in Acute Synovitis
por: Valdrighi, Natália, et al.
Publicado: (2023)

(68)Ga-NODAGA-Exendin-4 PET/CT Improves the Detection of Focal Congenital Hyperinsulinism
por: Boss, Marti, et al.
Publicado: (2022)

Complementary action of granulocyte macrophage colony-stimulating factor and interleukin-17A induces interleukin-23, receptor activator of nuclear factor-κB ligand, and matrix metalloproteinases and drives bone and cartilage pathology in experimental arthritis: rationale for combination therapy in rheumatoid arthritis
por: van Nieuwenhuijze, Annemarie E. M., et al.
Publicado: (2015)

Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer
por: Gotthardt, Martin, et al.
Publicado: (2018)

Carcinoembryonic antigen-targeted photodynamic therapy in colorectal cancer models
por: Elekonawo, Fortuné M. K., et al.
Publicado: (2019)

Cholesterol accumulation caused by low density lipoprotein receptor deficiency or a cholesterol-rich diet results in ectopic bone formation during experimental osteoarthritis
por: de Munter, Wouter, et al.
Publicado: (2013)

Alteration of the intestinal microbiome characterizes preclinical inflammatory arthritis in mice and its modulation attenuates established arthritis
por: Rogier, Rebecca, et al.
Publicado: (2017)

Supplementation of diet with non-digestible oligosaccharides alters the intestinal microbiota, but not arthritis development, in IL-1 receptor antagonist deficient mice
por: Rogier, Rebecca, et al.
Publicado: (2019)

Correction: Supplementation of diet with non-digestible oligosaccharides alters the intestinal microbiota, but not arthritis development, in IL-1 receptor antagonist deficient mice
por: Rogier, Rebecca, et al.
Publicado: (2019)

PET imaging during hypoglycaemia to study adipose tissue metabolism
por: Boss, Marti, et al.
Publicado: (2019)

Nox2 Deficiency Reduces Cartilage Damage and Ectopic Bone Formation in an Experimental Model for Osteoarthritis
por: Kruisbergen, Nik N. L., et al.
Publicado: (2021)

IL-1β-Mediated Activation of Adipose-Derived Mesenchymal Stromal Cells Results in PMN Reallocation and Enhanced Phagocytosis: A Possible Mechanism for the Reduction of Osteoarthritis Pathology
por: van Dalen, Stephanie C. M., et al.
Publicado: (2019)

Intracellular chemiluminescence activates targeted photodynamic destruction of leukaemic cells
por: Laptev, R, et al.
Publicado: (2006)

Potentiation of photodynamic therapy of cancer by complement: the effect of γ-inulin
por: Korbelik, M, et al.
Publicado: (2007)

Photodynamic therapy-generated vaccines: relevance of tumour cell death expression
por: Korbelik, M, et al.
Publicado: (2007)

Imaging and photodynamic therapy of prostate cancer using a theranostic PSMA-targeting ligand
por: Derks, Yvonne H. W., et al.
Publicado: (2023)

Local IL-18 gene transfer prevents severe joint destruction in murine collagen-induced arthritis by induction of IL-4 and osteoprotegerin
por: Joosten, LAB, et al.
Publicado: (2005)

Enhanced photodynamic destruction of a transplantable fibrosarcoma using photochemical internalisation of gelonin
por: Dietze, A, et al.
Publicado: (2005)

Interleukin-6 trans signalling enhances photodynamic therapy by modulating cell cycling
por: Wei, L-H, et al.
Publicado: (2007)

Photochemical internalisation of chemotherapy potentiates killing of multidrug-resistant breast and bladder cancer cells
por: Adigbli, D K, et al.
Publicado: (2007)

TRAIL-expressing mesenchymal stem cells kill the putative cancer stem cell population
por: Loebinger, M R, et al.
Publicado: (2010)

Targeting tumour energy metabolism potentiates the cytotoxicity of 5-aminolevulinic acid photodynamic therapy
por: Golding, J P, et al.
Publicado: (2013)

Huntington’s Disease: A Review of the Known PET Imaging Biomarkers and Targeting Radiotracers
por: Cybulska, Klaudia, et al.
Publicado: (2020)

The oncolytic effect in vivo of reovirus on tumour cells that have survived reovirus cell killing in vitro
por: Alain, T, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_ioeo4lbtv7niuh1p1hl74dch0s