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Annular Elastolytic Giant Cell Granuloma
Annular elastolytic giant cell granuloma (AEGCG) is a rare, often self-limiting chronic inflammatory disorder mostly occurring in the sun-exposed areas such as the dorsum of hands, extensor surfaces of arms, face, anterior neck, and upper chest. The pathognomonic histological findings include the pr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733766/ https://www.ncbi.nlm.nih.gov/pubmed/33329954 http://dx.doi.org/10.7759/cureus.11456 |
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author | Mistry, Anuja Mahesh Patel, Rutul Mistry, Mahesh Menon, Varna |
author_facet | Mistry, Anuja Mahesh Patel, Rutul Mistry, Mahesh Menon, Varna |
author_sort | Mistry, Anuja Mahesh |
collection | PubMed |
description | Annular elastolytic giant cell granuloma (AEGCG) is a rare, often self-limiting chronic inflammatory disorder mostly occurring in the sun-exposed areas such as the dorsum of hands, extensor surfaces of arms, face, anterior neck, and upper chest. The pathognomonic histological findings include the presence of numerous granulomas associated with loss of elastic fibers that appear to be ingested by multi-nucleated giant cells. Here, we present a case of a 56-year-old woman with multiple, anatomically variable erythematous lesions- annular and papular, mainly in the upper body. The clinical presentation and histopathologic findings support our diagnosis. |
format | Online Article Text |
id | pubmed-7733766 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-77337662020-12-15 Annular Elastolytic Giant Cell Granuloma Mistry, Anuja Mahesh Patel, Rutul Mistry, Mahesh Menon, Varna Cureus Dermatology Annular elastolytic giant cell granuloma (AEGCG) is a rare, often self-limiting chronic inflammatory disorder mostly occurring in the sun-exposed areas such as the dorsum of hands, extensor surfaces of arms, face, anterior neck, and upper chest. The pathognomonic histological findings include the presence of numerous granulomas associated with loss of elastic fibers that appear to be ingested by multi-nucleated giant cells. Here, we present a case of a 56-year-old woman with multiple, anatomically variable erythematous lesions- annular and papular, mainly in the upper body. The clinical presentation and histopathologic findings support our diagnosis. Cureus 2020-11-12 /pmc/articles/PMC7733766/ /pubmed/33329954 http://dx.doi.org/10.7759/cureus.11456 Text en Copyright © 2020, Mistry et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Dermatology Mistry, Anuja Mahesh Patel, Rutul Mistry, Mahesh Menon, Varna Annular Elastolytic Giant Cell Granuloma |
title | Annular Elastolytic Giant Cell Granuloma |
title_full | Annular Elastolytic Giant Cell Granuloma |
title_fullStr | Annular Elastolytic Giant Cell Granuloma |
title_full_unstemmed | Annular Elastolytic Giant Cell Granuloma |
title_short | Annular Elastolytic Giant Cell Granuloma |
title_sort | annular elastolytic giant cell granuloma |
topic | Dermatology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733766/ https://www.ncbi.nlm.nih.gov/pubmed/33329954 http://dx.doi.org/10.7759/cureus.11456 |
work_keys_str_mv | AT mistryanujamahesh annularelastolyticgiantcellgranuloma AT patelrutul annularelastolyticgiantcellgranuloma AT mistrymahesh annularelastolyticgiantcellgranuloma AT menonvarna annularelastolyticgiantcellgranuloma |