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Annular Elastolytic Giant Cell Granuloma

Annular elastolytic giant cell granuloma (AEGCG) is a rare, often self-limiting chronic inflammatory disorder mostly occurring in the sun-exposed areas such as the dorsum of hands, extensor surfaces of arms, face, anterior neck, and upper chest. The pathognomonic histological findings include the pr...

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Autores principales: Mistry, Anuja Mahesh, Patel, Rutul, Mistry, Mahesh, Menon, Varna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733766/
https://www.ncbi.nlm.nih.gov/pubmed/33329954
http://dx.doi.org/10.7759/cureus.11456
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author Mistry, Anuja Mahesh
Patel, Rutul
Mistry, Mahesh
Menon, Varna
author_facet Mistry, Anuja Mahesh
Patel, Rutul
Mistry, Mahesh
Menon, Varna
author_sort Mistry, Anuja Mahesh
collection PubMed
description Annular elastolytic giant cell granuloma (AEGCG) is a rare, often self-limiting chronic inflammatory disorder mostly occurring in the sun-exposed areas such as the dorsum of hands, extensor surfaces of arms, face, anterior neck, and upper chest. The pathognomonic histological findings include the presence of numerous granulomas associated with loss of elastic fibers that appear to be ingested by multi-nucleated giant cells. Here, we present a case of a 56-year-old woman with multiple, anatomically variable erythematous lesions- annular and papular, mainly in the upper body. The clinical presentation and histopathologic findings support our diagnosis.
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spelling pubmed-77337662020-12-15 Annular Elastolytic Giant Cell Granuloma Mistry, Anuja Mahesh Patel, Rutul Mistry, Mahesh Menon, Varna Cureus Dermatology Annular elastolytic giant cell granuloma (AEGCG) is a rare, often self-limiting chronic inflammatory disorder mostly occurring in the sun-exposed areas such as the dorsum of hands, extensor surfaces of arms, face, anterior neck, and upper chest. The pathognomonic histological findings include the presence of numerous granulomas associated with loss of elastic fibers that appear to be ingested by multi-nucleated giant cells. Here, we present a case of a 56-year-old woman with multiple, anatomically variable erythematous lesions- annular and papular, mainly in the upper body. The clinical presentation and histopathologic findings support our diagnosis. Cureus 2020-11-12 /pmc/articles/PMC7733766/ /pubmed/33329954 http://dx.doi.org/10.7759/cureus.11456 Text en Copyright © 2020, Mistry et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Mistry, Anuja Mahesh
Patel, Rutul
Mistry, Mahesh
Menon, Varna
Annular Elastolytic Giant Cell Granuloma
title Annular Elastolytic Giant Cell Granuloma
title_full Annular Elastolytic Giant Cell Granuloma
title_fullStr Annular Elastolytic Giant Cell Granuloma
title_full_unstemmed Annular Elastolytic Giant Cell Granuloma
title_short Annular Elastolytic Giant Cell Granuloma
title_sort annular elastolytic giant cell granuloma
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733766/
https://www.ncbi.nlm.nih.gov/pubmed/33329954
http://dx.doi.org/10.7759/cureus.11456
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AT patelrutul annularelastolyticgiantcellgranuloma
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AT menonvarna annularelastolyticgiantcellgranuloma