The Ig heavy chain protein but not its message controls early B cell development

Development of progenitor B cells (ProB cells) into precursor B cells (PreB cells) is dictated by immunoglobulin heavy chain checkpoint (IgHCC), where the IgHC encoded by a productively rearranged Igh allele assembles into a PreB cell receptor complex (PreBCR) to generate signals to initiate this tr...

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Detalles Bibliográficos
Autores principales: Aslam, Muhammad Assad, Alemdehy, Mir Farshid, Hao, Bingtao, Krijger, Peter H. L., Pritchard, Colin E. J., de Rink, Iris, Muhaimin, Fitriari Izzatunnisa, Nurzijah, Ika, van Baalen, Martijn, Kerkhoven, Ron M., van den Berk, Paul C. M., Skok, Jane A., Jacobs, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733823/
https://www.ncbi.nlm.nih.gov/pubmed/33229554
http://dx.doi.org/10.1073/pnas.2004810117

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