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KRAB zinc finger protein diversification drives mammalian interindividual methylation variability
Most transposable elements (TEs) in the mouse genome are heavily modified by DNA methylation and repressive histone modifications. However, a subset of TEs exhibit variable methylation levels in genetically identical individuals, and this is associated with epigenetically conferred phenotypic differ...
Autores principales: | Bertozzi, Tessa M., Elmer, Jessica L., Macfarlan, Todd S., Ferguson-Smith, Anne C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733849/ https://www.ncbi.nlm.nih.gov/pubmed/33239447 http://dx.doi.org/10.1073/pnas.2017053117 |
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