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Expansion of a Specific Plasmodium falciparum PfMDR1 Haplotype in Southeast Asia with Increased Substrate Transport

Artemisinin-based combination therapies (ACTs) have been vital in reducing malaria mortality rates since the 2000s. Their efficacy, however, is threatened by the emergence and spread of artemisinin resistance in Southeast Asia. The Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) transp...

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Detalles Bibliográficos
Autores principales:	Calçada, Carla, Silva, Miguel, Baptista, Vitória, Thathy, Vandana, Silva-Pedrosa, Rita, Granja, Diana, Ferreira, Pedro Eduardo, Gil, José Pedro, Fidock, David A., Veiga, Maria Isabel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733942/ https://www.ncbi.nlm.nih.gov/pubmed/33262257 http://dx.doi.org/10.1128/mBio.02093-20

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