A Screen-Printed Electrode Modified With Graphene/Co(3)O(4) Nanocomposite for Electrochemical Detection of Tramadol

In this paper, graphene (Gr)/Co(3)O(4) nanocomposite was synthesized and utilized for the development of a novel electrochemical sensor to detect tramadol. Tramadol determination was examined by linear sweep voltammetry, differential pulse voltammetry, cyclic voltammetry, and chronoamperometry on Gr...

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Detalles Bibliográficos
Autores principales: Aflatoonian, Mohammad Reza, Tajik, Somayeh, Aflatoonian, Behnaz, Beitollahi, Hadi, Zhang, Kaiqiang, Le, Quyet Van, Cha, Joo Hwan, Jang, Ho Won, Shokouhimehr, Mohammadreza, Peng, Wanxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734144/
https://www.ncbi.nlm.nih.gov/pubmed/33330356
http://dx.doi.org/10.3389/fchem.2020.562308
Descripción
Sumario:In this paper, graphene (Gr)/Co(3)O(4) nanocomposite was synthesized and utilized for the development of a novel electrochemical sensor to detect tramadol. Tramadol determination was examined by linear sweep voltammetry, differential pulse voltammetry, cyclic voltammetry, and chronoamperometry on Gr/Co(3)O(4) nanocomposite-modified screen-printed electrode (Gr/Co(3)O(4)/SPE) in phosphate-buffered saline (PBS). Under the optimized condition, the detection limit of tramadol is 0.03 μM (S/N = 3) in the linear ranges of 0.1–500.0 μM. Furthermore, Gr/Co(3)O(4)/SPE was satisfactorily utilized to detect tramadol in tramadol tablet and urine specimens.

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