Interstitial pneumonitis related to trastuzumab deruxtecan, a human epidermal growth factor receptor 2‐targeting Ab–drug conjugate, in monkeys

Trastuzumab deruxtecan (T‐DXd: DS‐8201a) is an anti‐human epidermal growth factor receptor 2 (HER2) Ab–drug conjugated with deruxtecan (DXd), a derivative of exatecan. The objective of this study was to characterize T‐DXd‐induced lung toxicity in cynomolgus monkeys. Trastuzumab deruxtecan was inject...

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Detalles Bibliográficos
Autores principales: Kumagai, Kazuyoshi, Aida, Tetsuo, Tsuchiya, Yoshimi, Kishino, Yuki, Kai, Kiyonori, Mori, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734153/
https://www.ncbi.nlm.nih.gov/pubmed/33051938
http://dx.doi.org/10.1111/cas.14686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734153/
https://www.ncbi.nlm.nih.gov/pubmed/33051938
http://dx.doi.org/10.1111/cas.14686

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