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IGLR-2, a Leucine-Rich Repeat Domain Containing Protein, Is Required for the Host Defense in Caenorhabditis elegans

Enterohemorrhagic Escherichia coli (EHEC), a human pathogen, also infects Caenorhabditis elegans. We demonstrated previously that C. elegans activates the p38 MAPK innate immune pathway to defend against EHEC infection. However, whether a C. elegans pattern recognition receptor (PRR) exists to regul...

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Detalles Bibliográficos
Autores principales: Kuo, Cheng-Ju, Hsu, Ya-Chu, Wang, Sin-Tian, Liou, Bang-Yu, Lim, Serene Boon-Yuean, Chen, Yi-Wei, Chen, Chang-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734252/
https://www.ncbi.nlm.nih.gov/pubmed/33329523
http://dx.doi.org/10.3389/fimmu.2020.561337