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PD-L1-Mediated Immunosuppression in Glioblastoma Is Associated With the Infiltration and M2-Polarization of Tumor-Associated Macrophages

There has been no significant improvements for immune checkpoint inhibitors since its first use. Tumour-associated macrophages (TAMs) are critical mediators in the PD-1/PD-L1 axis, contributing to the immunosuppressive tumour microenvironment. This study aims to investigate the potential role of PD-...

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Detalles Bibliográficos
Autores principales:	Zhu, Zhiyuan, Zhang, Hongbo, Chen, Baodong, Liu, Xing, Zhang, Shizhong, Zong, Zhitao, Gao, Mengqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734279/ https://www.ncbi.nlm.nih.gov/pubmed/33329573 http://dx.doi.org/10.3389/fimmu.2020.588552

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