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Pharmacological Programming of Endosomal Signaling Activated by Small Molecule Ligands of the Follicle Stimulating Hormone Receptor

Follicle-stimulating hormone receptor (FSHR) is a G protein-coupled receptor (GPCR) with pivotal roles in reproduction. One key mechanism dictating the signal activity of GPCRs is membrane trafficking. After binding its hormone FSH, FSHR undergoes internalization to very early endosomes (VEEs) for i...

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Detalles Bibliográficos
Autores principales:	Sposini, Silvia, De Pascali, Francesco, Richardson, Rachel, Sayers, Niamh S., Perrais, David, Yu, Henry N., Palmer, Stephen, Nataraja, Selva, Reiter, Eric, Hanyaloglu, Aylin C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734412/ https://www.ncbi.nlm.nih.gov/pubmed/33329002 http://dx.doi.org/10.3389/fphar.2020.593492

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