Cargando…
Endoplasmic reticulum stress induces hepatic plasminogen activator inhibitor 1 in murine nonalcoholic steatohepatitis
Plasminogen activator inhibitor 1 (PAI‐1) is a stress‐responsive gene that is highly induced in nonalcoholic steatohepatitis (NASH). Endoplasmic reticulum (ER) stress is a salient feature of NASH, yet it is unknown whether ER stress contributes to hepatic PAI‐1 induction in this disorder. Therefore,...
Autores principales: | Olivares, Shantel, Henkel, Anne S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734423/ https://www.ncbi.nlm.nih.gov/pubmed/33336157 http://dx.doi.org/10.1096/fba.2020-00056 |
Ejemplares similares
-
Inhibition of Plasminogen Activator Inhibitor 1 Attenuates Hepatic Steatosis but Does Not Prevent Progressive Nonalcoholic Steatohepatitis in Mice
por: Henkel, Anne S., et al.
Publicado: (2018) -
Endoplasmic Reticulum Stress Regulates Hepatic Bile Acid Metabolism in Mice
por: Henkel, Anne S., et al.
Publicado: (2016) -
Endoplasmic Reticulum Stress Activates the Hepatic Activator Protein 1 Complex via Mitogen Activated Protein Kinase-Dependent Signaling Pathways
por: Olivares, Shantel, et al.
Publicado: (2014) -
Simvastatin Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in Nonalcoholic Steatohepatitis Experimental Model
por: Rodrigues, Graziella, et al.
Publicado: (2019) -
CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis
por: Willy, Jeffrey A., et al.
Publicado: (2015)