Cargando…

Astrocyte Glutamate Uptake and Water Homeostasis Are Dysregulated in the Hippocampus of Multiple Sclerosis Patients With Seizures

While seizure disorders are more prevalent among multiple sclerosis (MS) patients than the population overall and prognosticate earlier death & disability, their etiology remains unclear. Translational data indicate perturbed expression of astrocytic molecules contributing to homeostatic neurona...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lapato, Andrew S., Thompson, Sarah M., Parra, Karen, Tiwari-Woodruff, Seema K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734542/ https://www.ncbi.nlm.nih.gov/pubmed/33297722 http://dx.doi.org/10.1177/1759091420979604

Ejemplares similares

Astrocytes Maintain Glutamate Homeostasis in the CNS by Controlling the Balance between Glutamate Uptake and Release
por: Mahmoud, Shaimaa, et al.
Publicado: (2019)

Dysregulation of Ambient Glutamate and Glutamate Receptors in Epilepsy: An Astrocytic Perspective
por: Alcoreza, Oscar B., et al.
Publicado: (2021)

Astroglial Glutamate Signaling and Uptake in the Hippocampus
por: Rose, Christine R., et al.
Publicado: (2018)

NLRX1 Enhances Glutamate Uptake and Inhibits Glutamate Release by Astrocytes
por: Mahmoud, Shaimaa, et al.
Publicado: (2019)

Lesion-Induced Alterations in Astrocyte Glutamate Transporter Expression and Function in the Hippocampus
por: Schreiner, Alexandra E., et al.
Publicado: (2013)

Astrocytes revisited: concise historic outlook on glutamate homeostasis and signaling
por: Parpura, Vladimir, et al.
Publicado: (2012)

Astrocyte Glutamate Uptake and Signaling as Novel Targets for Antiepileptogenic Therapy
por: Peterson, Allison R., et al.
Publicado: (2020)

Perineuronal nets support astrocytic ion and glutamate homeostasis at tripartite synapses
por: Tewari, Bhanu P., et al.
Publicado: (2023)

Glutamate Uptake Triggers Transporter-Mediated GABA Release from Astrocytes
por: Héja, László, et al.
Publicado: (2009)

β-Catenin signaling positively regulates glutamate uptake and metabolism in astrocytes
por: Lutgen, Victoria, et al.
Publicado: (2016)

Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory
por: Nguyen, Amanda Q., et al.
Publicado: (2020)

Dysregulation of Astrocytic HMGB1 Signaling in Amyotrophic Lateral Sclerosis
por: Brambilla, Liliana, et al.
Publicado: (2018)

Analogues of ERβ ligand chloroindazole exert immunomodulatory and remyelinating effects in a mouse model of multiple sclerosis
por: Karim, Hawra, et al.
Publicado: (2019)

The Key Role of Astrocytes in Amyotrophic Lateral Sclerosis and Their Commitment to Glutamate Excitotoxicity
por: Provenzano, Francesca, et al.
Publicado: (2023)

Circadian Modulation of Gene Expression, but not Glutamate Uptake, in Mouse and Rat Cortical Astrocytes
por: Beaulé, Christian, et al.
Publicado: (2009)

PAR1 activation induces rapid changes in glutamate uptake and astrocyte morphology
por: Sweeney, Amanda M., et al.
Publicado: (2017)

Dysregulation of Astrocyte Ion Homeostasis and Its Relevance for Stroke-Induced Brain Damage
por: van Putten, Michel J.A.M., et al.
Publicado: (2021)

Age-Associated Upregulation of Glutamate Transporters and Glutamine Synthetase in Senescent Astrocytes In Vitro and in the Mouse and Human Hippocampus
por: Matias, Isadora, et al.
Publicado: (2023)

Comparison of the Effects of Yokukansan and Yokukansankachimpihange on Glutamate Uptake by Cultured Astrocytes and Glutamate-Induced Excitotoxicity in Cultured PC12 Cells
por: Kawakami, Zenji, et al.
Publicado: (2019)

Increase in chemokine CXCL1 by ERβ ligand treatment is a key mediator in promoting axon myelination
por: Karim, Hawra, et al.
Publicado: (2018)

Methylglyoxal Induces Changes in the Glyoxalase System and Impairs Glutamate Uptake Activity in Primary Astrocytes
por: Hansen, Fernanda, et al.
Publicado: (2017)

K(+) efflux through postsynaptic NMDA receptors suppresses local astrocytic glutamate uptake
por: Tyurikova, Olga, et al.
Publicado: (2022)

CCL5–Glutamate Cross-Talk in Astrocyte-Neuron Communication in Multiple Sclerosis
por: Pittaluga, Anna
Publicado: (2017)

Plasminogen activator system homeostasis and its dysregulation by ethanol in astrocyte cultures and the developing brain
por: Wilhelm, Clare J., et al.
Publicado: (2018)

Role of Microglia and Astrocytes in Alzheimer’s Disease: From Neuroinflammation to Ca(2+) Homeostasis Dysregulation
por: Di Benedetto, Giulia, et al.
Publicado: (2022)

A Computational Model to Investigate Astrocytic Glutamate Uptake Influence on Synaptic Transmission and Neuronal Spiking
por: Allam, Sushmita L., et al.
Publicado: (2012)

Long-term NMDAR antagonism correlates reduced astrocytic glutamate uptake with anxiety-like phenotype
por: Zimmer, Eduardo R., et al.
Publicado: (2015)

Oncostatin M promotes excitotoxicity by inhibiting glutamate uptake in astrocytes: implications in HIV-associated neurotoxicity
por: Moidunny, Shamsudheen, et al.
Publicado: (2016)

An iPSC-derived astrocyte model of fragile X syndrome exhibits dysregulated cholesterol homeostasis
por: Talvio, Karo, et al.
Publicado: (2023)

Distribution of Extracellular Glutamate in the Neuropil of Hippocampus
por: Herman, Melissa A., et al.
Publicado: (2011)

Corrigendum: Long-term NMDAR antagonism correlates reduced astrocytic glutamate uptake with anxiety-like phenotype
por: Zimmer, Eduardo R., et al.
Publicado: (2016)

Role of Na,K-ATPase α1 and α2 Isoforms in the Support of Astrocyte Glutamate Uptake
por: Illarionava, Nina B., et al.
Publicado: (2014)

The non-adrenergic imidazoline-1 receptor protein nischarin is a key regulator of astrocyte glutamate uptake
por: Gupta, Swati, et al.
Publicado: (2022)

HIV Nef Expression Down-modulated GFAP Expression and Altered Glutamate Uptake and Release and Proliferation in Astrocytes
por: Wilson, Kelly M., et al.
Publicado: (2023)

Computational model of neuron-astrocyte interactions during focal seizure generation
por: Reato, Davide, et al.
Publicado: (2012)

Astrocytic Regulation of Glutamate Transmission in Schizophrenia
por: Mei, Yu-Ying, et al.
Publicado: (2018)

Glutamate-glutamine homeostasis is perturbed in neurons and astrocytes derived from patient iPSC models of frontotemporal dementia
por: Aldana, Blanca I., et al.
Publicado: (2020)

Regulation of glutamate homeostasis in the nucleus accumbens by astrocytic CB1 receptors and its role in cocaine-motivated behaviors
por: Zhang, Lan-Yuan, et al.
Publicado: (2022)

Dysregulated Homeostasis of Acetylcholine Levels in Immune Cells of RR-Multiple Sclerosis Patients
por: Di Bari, Maria, et al.
Publicado: (2016)

Laser-scanning astrocyte mapping reveals increased glutamate-responsive domain size and disrupted maturation of glutamate uptake following neonatal cortical freeze-lesion
por: Armbruster, Moritz, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_9kqd7vrrufo6ma9pp7h864p963