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SARS-CoV‑2, a virus with many faces: a series of cases with prolonged persistence of COVID-19 symptoms

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as the causative agent of the ongoing pandemic, has spread into more than 200 countries to date. The disease which is caused by the virus is termed COVID-19. In most cases, it presents at first like common flu with cough and other respira...

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Autores principales: Sofian, Masoomeh, Velayati, Ali Akbar, Banifazl, Mohammad, Fotouhi, Fatemeh, Sadat Larijani, Mona, Afzali, Neda, Ramezani, Amitis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734614/
https://www.ncbi.nlm.nih.gov/pubmed/33315163
http://dx.doi.org/10.1007/s10354-020-00793-8
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author Sofian, Masoomeh
Velayati, Ali Akbar
Banifazl, Mohammad
Fotouhi, Fatemeh
Sadat Larijani, Mona
Afzali, Neda
Ramezani, Amitis
author_facet Sofian, Masoomeh
Velayati, Ali Akbar
Banifazl, Mohammad
Fotouhi, Fatemeh
Sadat Larijani, Mona
Afzali, Neda
Ramezani, Amitis
author_sort Sofian, Masoomeh
collection PubMed
description Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as the causative agent of the ongoing pandemic, has spread into more than 200 countries to date. The disease which is caused by the virus is termed COVID-19. In most cases, it presents at first like common flu with cough and other respiratory symptoms. Nevertheless, other symptoms have been reported, such as a feeling of extreme fatigue, gastrointestinal symptoms, or acute onset of olfactory and gustatory dysfunction. Here we report a series of 10 cases (1 male, 9 females) observed between February and April 2020, with an undulating appearance and disappearance of symptoms. Weeks passed before the diagnosis was established. Symptoms resolved rapidly after treatment with hydroxychloroquine. It seems that the course of COVID-19 can be mild or moderate but with a long persistence of symptoms, and may therefore remain obscure. This may cause a public health issue because of the long infectivity of these patients.
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spelling pubmed-77346142020-12-14 SARS-CoV‑2, a virus with many faces: a series of cases with prolonged persistence of COVID-19 symptoms Sofian, Masoomeh Velayati, Ali Akbar Banifazl, Mohammad Fotouhi, Fatemeh Sadat Larijani, Mona Afzali, Neda Ramezani, Amitis Wien Med Wochenschr Short Report Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as the causative agent of the ongoing pandemic, has spread into more than 200 countries to date. The disease which is caused by the virus is termed COVID-19. In most cases, it presents at first like common flu with cough and other respiratory symptoms. Nevertheless, other symptoms have been reported, such as a feeling of extreme fatigue, gastrointestinal symptoms, or acute onset of olfactory and gustatory dysfunction. Here we report a series of 10 cases (1 male, 9 females) observed between February and April 2020, with an undulating appearance and disappearance of symptoms. Weeks passed before the diagnosis was established. Symptoms resolved rapidly after treatment with hydroxychloroquine. It seems that the course of COVID-19 can be mild or moderate but with a long persistence of symptoms, and may therefore remain obscure. This may cause a public health issue because of the long infectivity of these patients. Springer Vienna 2020-12-14 2021 /pmc/articles/PMC7734614/ /pubmed/33315163 http://dx.doi.org/10.1007/s10354-020-00793-8 Text en © Springer-Verlag GmbH Austria, ein Teil von Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Short Report
Sofian, Masoomeh
Velayati, Ali Akbar
Banifazl, Mohammad
Fotouhi, Fatemeh
Sadat Larijani, Mona
Afzali, Neda
Ramezani, Amitis
SARS-CoV‑2, a virus with many faces: a series of cases with prolonged persistence of COVID-19 symptoms
title SARS-CoV‑2, a virus with many faces: a series of cases with prolonged persistence of COVID-19 symptoms
title_full SARS-CoV‑2, a virus with many faces: a series of cases with prolonged persistence of COVID-19 symptoms
title_fullStr SARS-CoV‑2, a virus with many faces: a series of cases with prolonged persistence of COVID-19 symptoms
title_full_unstemmed SARS-CoV‑2, a virus with many faces: a series of cases with prolonged persistence of COVID-19 symptoms
title_short SARS-CoV‑2, a virus with many faces: a series of cases with prolonged persistence of COVID-19 symptoms
title_sort sars-cov‑2, a virus with many faces: a series of cases with prolonged persistence of covid-19 symptoms
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734614/
https://www.ncbi.nlm.nih.gov/pubmed/33315163
http://dx.doi.org/10.1007/s10354-020-00793-8
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