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A case report: rapid progression of coronary atherosclerosis in a patient taking Targretin (Bexarotene)

Anti-neoplastic drugs have made major advancements in oncology, however they are not without cardiovascular consequences. We present a patient with cutaneous T-cell lymphoma receiving Targretin therapy who presented with accelerated atherosclerosis. His triglyceride level (TG) was greater than 1000 ...

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Detalles Bibliográficos
Autores principales: DeAngelo, Sean, Mann, Kailyn I., Abdulbasit, Muhammad, Ahnert, Amy, Sundlöf, Deborah W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734706/
https://www.ncbi.nlm.nih.gov/pubmed/33308287
http://dx.doi.org/10.1186/s40959-020-00087-3
Descripción
Sumario:Anti-neoplastic drugs have made major advancements in oncology, however they are not without cardiovascular consequences. We present a patient with cutaneous T-cell lymphoma receiving Targretin therapy who presented with accelerated atherosclerosis. His triglyceride level (TG) was greater than 1000 mg/dL, which rapidly improved with discontinuation of Targretin.