A case report: rapid progression of coronary atherosclerosis in a patient taking Targretin (Bexarotene)

Anti-neoplastic drugs have made major advancements in oncology, however they are not without cardiovascular consequences. We present a patient with cutaneous T-cell lymphoma receiving Targretin therapy who presented with accelerated atherosclerosis. His triglyceride level (TG) was greater than 1000 ...

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Autores principales: DeAngelo, Sean, Mann, Kailyn I., Abdulbasit, Muhammad, Ahnert, Amy, Sundlöf, Deborah W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734706/
https://www.ncbi.nlm.nih.gov/pubmed/33308287
http://dx.doi.org/10.1186/s40959-020-00087-3
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author DeAngelo, Sean
Mann, Kailyn I.
Abdulbasit, Muhammad
Ahnert, Amy
Sundlöf, Deborah W.
author_facet DeAngelo, Sean
Mann, Kailyn I.
Abdulbasit, Muhammad
Ahnert, Amy
Sundlöf, Deborah W.
author_sort DeAngelo, Sean
collection PubMed
description Anti-neoplastic drugs have made major advancements in oncology, however they are not without cardiovascular consequences. We present a patient with cutaneous T-cell lymphoma receiving Targretin therapy who presented with accelerated atherosclerosis. His triglyceride level (TG) was greater than 1000 mg/dL, which rapidly improved with discontinuation of Targretin.
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spelling pubmed-77347062020-12-15 A case report: rapid progression of coronary atherosclerosis in a patient taking Targretin (Bexarotene) DeAngelo, Sean Mann, Kailyn I. Abdulbasit, Muhammad Ahnert, Amy Sundlöf, Deborah W. Cardiooncology Short Communication Anti-neoplastic drugs have made major advancements in oncology, however they are not without cardiovascular consequences. We present a patient with cutaneous T-cell lymphoma receiving Targretin therapy who presented with accelerated atherosclerosis. His triglyceride level (TG) was greater than 1000 mg/dL, which rapidly improved with discontinuation of Targretin. BioMed Central 2020-12-14 /pmc/articles/PMC7734706/ /pubmed/33308287 http://dx.doi.org/10.1186/s40959-020-00087-3 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Short Communication
DeAngelo, Sean
Mann, Kailyn I.
Abdulbasit, Muhammad
Ahnert, Amy
Sundlöf, Deborah W.
A case report: rapid progression of coronary atherosclerosis in a patient taking Targretin (Bexarotene)
title A case report: rapid progression of coronary atherosclerosis in a patient taking Targretin (Bexarotene)
title_full A case report: rapid progression of coronary atherosclerosis in a patient taking Targretin (Bexarotene)
title_fullStr A case report: rapid progression of coronary atherosclerosis in a patient taking Targretin (Bexarotene)
title_full_unstemmed A case report: rapid progression of coronary atherosclerosis in a patient taking Targretin (Bexarotene)
title_short A case report: rapid progression of coronary atherosclerosis in a patient taking Targretin (Bexarotene)
title_sort case report: rapid progression of coronary atherosclerosis in a patient taking targretin (bexarotene)
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734706/
https://www.ncbi.nlm.nih.gov/pubmed/33308287
http://dx.doi.org/10.1186/s40959-020-00087-3
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