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Overexpression of astroglial major histocompatibility complex class I in the medial prefrontal cortex impairs visual discrimination learning in mice
BACKGROUND: Immune molecules, such as cytokines, complement, and major histocompatibility complex (MHC) proteins, in the central nervous system are often associated with neuropsychiatric disorders. Neuronal MHC class I (MHCI), such as H-2D, regulate neurite outgrowth, the establishment and function...
Autores principales: | Wulaer, Bolati, Hada, Kazuhiro, Sobue, Akira, Itoh, Norimichi, Nabeshima, Toshitaka, Nagai, Taku, Yamada, Kiyofumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734728/ https://www.ncbi.nlm.nih.gov/pubmed/33317605 http://dx.doi.org/10.1186/s13041-020-00710-5 |
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