Cooperative synaptic and intrinsic plasticity in a disynaptic limbic circuit drive stress-induced anhedonia and passive coping in mice

Stress promotes negative affective states, which include anhedonia and passive coping. While these features are in part mediated by neuroadaptations in brain reward circuitry, a comprehensive framework of how stress-induced negative affect may be encoded within key nodes of this circuit is lacking....

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Detalles Bibliográficos
Autores principales: Pignatelli, Marco, Tejeda, Hugo A., Barker, David J., Bontempi, Leonardo, Wu, Jocelyn, Lopez, Alejandra, Palma Ribeiro, Sissi, Lucantonio, Federica, Parise, Eric M., Torres-Berrio, Angélica, Alvarez-Bagnarol, Yocasta, Marino, Rosa A. M., Cai, Zhao-Lin, Xue, Mingshan, Morales, Marisela, Tamminga, Carol A., Nestler, Eric J., Bonci, Antonello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735389/
https://www.ncbi.nlm.nih.gov/pubmed/32161361
http://dx.doi.org/10.1038/s41380-020-0686-8

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