Missing value imputation in proximity extension assay-based targeted proteomics data

Targeted proteomics utilizing antibody-based proximity extension assays provides sensitive and highly specific quantifications of plasma protein levels. Multivariate analysis of this data is hampered by frequent missing values (random or left censored), calling for imputation approaches. While appro...

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Detalles Bibliográficos
Autores principales: Lenz, Michael, Schulz, Andreas, Koeck, Thomas, Rapp, Steffen, Nagler, Markus, Sauer, Madeleine, Eggebrecht, Lisa, Ten Cate, Vincent, Panova-Noeva, Marina, Prochaska, Jürgen H., Lackner, Karl J., Münzel, Thomas, Leineweber, Kirsten, Wild, Philipp S., Andrade-Navarro, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735586/
https://www.ncbi.nlm.nih.gov/pubmed/33315883
http://dx.doi.org/10.1371/journal.pone.0243487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735586/
https://www.ncbi.nlm.nih.gov/pubmed/33315883
http://dx.doi.org/10.1371/journal.pone.0243487

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