Cargando…

Missing value imputation in proximity extension assay-based targeted proteomics data

Targeted proteomics utilizing antibody-based proximity extension assays provides sensitive and highly specific quantifications of plasma protein levels. Multivariate analysis of this data is hampered by frequent missing values (random or left censored), calling for imputation approaches. While appro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lenz, Michael, Schulz, Andreas, Koeck, Thomas, Rapp, Steffen, Nagler, Markus, Sauer, Madeleine, Eggebrecht, Lisa, Ten Cate, Vincent, Panova-Noeva, Marina, Prochaska, Jürgen H., Lackner, Karl J., Münzel, Thomas, Leineweber, Kirsten, Wild, Philipp S., Andrade-Navarro, Miguel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735586/ https://www.ncbi.nlm.nih.gov/pubmed/33315883 http://dx.doi.org/10.1371/journal.pone.0243487

Ejemplares similares

Comprehensive platelet phenotyping supports the role of platelets in the pathogenesis of acute venous thromboembolism – results from clinical observation studies
por: Panova-Noeva, Marina, et al.
Publicado: (2020)

Specialized Management of Oral Anticoagulation Therapy Improves Outcome in Patients with Chronic Renal Insufficiency
por: Lauterbach, Michael, et al.
Publicado: (2020)

Telemedicine-Based Specialized Care Improves the Outcome of Anticoagulated Individuals with Venous Thromboembolism—Results from the thrombEVAL Study
por: Keller, Karsten, et al.
Publicado: (2020)

Association of FXI activity with thrombo-inflammation, extracellular matrix, lipid metabolism and apoptosis in venous thrombosis
por: Pallares Robles, Alejandro, et al.
Publicado: (2022)

Cost saving analysis of specialized, eHealth-based management of patients receiving oral anticoagulation therapy: Results from the thrombEVAL study
por: Eggebrecht, Lisa, et al.
Publicado: (2021)

Characterization of Thrombin Generation Curve Shape in Presence of Platelets from Acute Venous Thromboembolism Patients
por: Lagrange, Jeremy, et al.
Publicado: (2020)

Age-related diagnostic value of D-dimer testing and the role of inflammation in patients with suspected deep vein thrombosis
por: Prochaska, Jürgen H., et al.
Publicado: (2017)

Clinical profile and outcome of isolated pulmonary embolism: a systematic review and meta-analysis
por: ten Cate, Vincent, et al.
Publicado: (2023)

The impact of platelet indices on clinical outcome in heart failure: results from the MyoVasc study
por: Dahlen, Bianca, et al.
Publicado: (2021)

Relationships between coagulation factors and thrombin generation in a general population with arterial and venous disease background
por: van Paridon, Pauline C. S., et al.
Publicado: (2022)

Lower levels of vWF are associated with lower risk of cardiovascular disease
por: van Paridon, Pauline C. S., et al.
Publicado: (2022)

Mean Platelet Volume and Arterial Stiffness – Clinical Relationship and Common Genetic Variability
por: Panova-Noeva, Marina, et al.
Publicado: (2017)

Sex-Specific Relationship Between Parathyroid Hormone and Platelet Indices in Phenotypes of Heart Failure—Results From the MyoVasc Study
por: Dahlen, Bianca, et al.
Publicado: (2021)

Renin, aldosterone, the aldosterone-to-renin ratio, and incident hypertension among normotensive subjects from the general population
por: Arnold, Natalie, et al.
Publicado: (2022)

Thrombin generation in cardiovascular disease and mortality – results from the Gutenberg Health Study
por: van Paridon, Pauline C.S., et al.
Publicado: (2019)

Cigarette Smoking Is Related to Endothelial Dysfunction of Resistance, but Not Conduit Arteries in the General Population—Results From the Gutenberg Health Study
por: Hahad, Omar, et al.
Publicado: (2021)

Relation between platelet coagulant and vascular function, sex-specific analysis in adult survivors of childhood cancer compared to a population-based sample
por: Panova-Noeva, Marina, et al.
Publicado: (2019)

Intake of Vitamin K Antagonists and Worsening of Cardiac and Vascular Disease: Results From the Population‐Based Gutenberg Health Study
por: Eggebrecht, Lisa, et al.
Publicado: (2018)

Imputation of missing genotypes: an empirical evaluation of IMPUTE
por: Zhao, Zhenming, et al.
Publicado: (2008)

Clinical Applications, Pitfalls, and Uncertainties of Thrombin Generation in the Presence of Platelets
por: Panova-Noeva, Marina, et al.
Publicado: (2019)

Galectin-3 for prediction of cardiac function compared to NT-proBNP in individuals with prediabetes and type 2 diabetes mellitus
por: Schmitt, Volker H., et al.
Publicado: (2021)

Missing Data and Imputation Methods
por: Schober, Patrick, et al.
Publicado: (2020)

Cardiovascular profiling in the diabetic continuum: results from the population-based Gutenberg Health Study
por: Schmitt, Volker H., et al.
Publicado: (2021)

Promotion of Arterial Stiffness by Childhood Cancer and Its Characteristics in Adult Long‐Term Survivors
por: Arnold, Natalie, et al.
Publicado: (2021)

Flexible imputation of missing data
por: van Buuren, Stef
Publicado: (2018)

Disturbed Glucose Metabolism and Left Ventricular Geometry in the General Population
por: Schmitt, Volker H., et al.
Publicado: (2021)

Missing value imputation in high-dimensional phenomic data: imputable or not, and how?
por: Liao, Serena G, et al.
Publicado: (2014)

Missing value imputation for epistatic MAPs
por: Ryan, Colm, et al.
Publicado: (2010)

Imputing missing distances in molecular phylogenetics
por: Xia, Xuhua
Publicado: (2018)

The Frailty Index, Missing Data, and Imputation
por: Pridham, Glen, et al.
Publicado: (2020)

DNA methylation and cardiovascular disease in humans: a systematic review and database of known CpG methylation sites
por: Krolevets, Mykhailo, et al.
Publicado: (2023)

Imputing missing genotypes: effects of methods and patterns of missing data
por: Ogut, Funda, et al.
Publicado: (2011)

Midregional pro atrial natriuretic peptide: a novel important biomarker for noise annoyance-induced cardiovascular morbidity and mortality?
por: Hahad, Omar, et al.
Publicado: (2020)

Editorial: Role of the Platelet Phenomenon in Cardiovascular Diseases and Cancer
por: Panova-Noeva, Marina, et al.
Publicado: (2022)

Editorial: Women in thrombosis
por: Whyte, Claire S., et al.
Publicado: (2023)

Effects of empagliflozin on left ventricular diastolic function in addition to usual care in individuals with type 2 diabetes mellitus—results from the randomized, double-blind, placebo-controlled EmDia trial
por: Prochaska, Jürgen H., et al.
Publicado: (2023)

Multiple imputation of missing data using SAS
por: Berglund, Patricia A, et al.
Publicado: (2014)

Imputation methods for missing data for polygenic models
por: Fridley, Brooke, et al.
Publicado: (2003)

Imputing missing covariate values for the Cox model
por: White, Ian R, et al.
Publicado: (2009)

SICE: an improved missing data imputation technique
por: Khan, Shahidul Islam, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_hs36n9cmm2b2oo0837gc3ho176