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Impact of scaling up dolutegravir on antiretroviral resistance in South Africa: A modeling study

BACKGROUND: Rising resistance of HIV-1 to non-nucleoside reverse transcriptase inhibitors (NNRTIs) threatens the success of the global scale-up of antiretroviral therapy (ART). The switch to WHO-recommended dolutegravir (DTG)-based regimens could reduce this threat due to DTG’s high genetic barrier...

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Detalles Bibliográficos
Autores principales:	Hauser, Anthony, Kusejko, Katharina, Johnson, Leigh F., Günthard, Huldrych F., Riou, Julien, Wandeler, Gilles, Egger, Matthias, Kouyos, Roger D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735592/ https://www.ncbi.nlm.nih.gov/pubmed/33315863 http://dx.doi.org/10.1371/journal.pmed.1003397

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