Host RAB11FIP5 protein inhibits the release of Kaposi’s sarcoma-associated herpesvirus particles by promoting lysosomal degradation of ORF45

Open reading frame (ORF) 45 is an outer tegument protein of Kaposi’s sarcoma-associated herpesvirus (KSHV). Genetic analysis of an ORF45-null mutant revealed that ORF45 plays a key role in the events leading to the release of KSHV particles. ORF45 associates with lipid rafts (LRs), which is responsi...

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Detalles Bibliográficos
Autores principales: Wei, Xiaoqin, Dong, Jiazhen, Cheng, Chin-Chen, Ji, Mingjun, Yu, Lei, Luo, Shengqiu, Wu, Shuwen, Bai, Lei, Lan, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735600/
https://www.ncbi.nlm.nih.gov/pubmed/33315947
http://dx.doi.org/10.1371/journal.ppat.1009099

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