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Synthesis and analysis of 4-(3-fluoropropyl)-glutamic acid stereoisomers to determine the stereochemical purity of (4S)-4-(3-[(18)F]fluoropropyl)-L-glutamic acid ([(18)F]FSPG) for clinical use

(4S)-4-(3-[(18)F]Fluoropropyl)-L-glutamic acid ([(18)F]FSPG) is a positron emission tomography (PET) imaging agent for measuring the system x(C)(−) transporter activity. It has been used for the detection of various cancers and metastasis in clinical trials. [(18)F]FSPG is also a promising diagnosti...

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Detalles Bibliográficos
Autores principales:	Shih, Kai-Ting, Huang, Ya-Yao, Yang, Chia-Ying, Cheng, Mei-Fang, Tien, Yu-Wen, Shiue, Chyng-Yann, Yen, Rouh-Fang, Hsin, Ling-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735610/ https://www.ncbi.nlm.nih.gov/pubmed/33315962 http://dx.doi.org/10.1371/journal.pone.0243831

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