The antihypertensive agent hydralazine reduced extracellular matrix synthesis and liver fibrosis in nonalcoholic steatohepatitis exacerbated by hypertension

Hypertension is an important risk factor for nonalcoholic steatohepatitis. We have previously demonstrated that hypertensive rats fed a high fat and cholesterol (HFC) diet incurred a more severe hepatic inflammatory response and fibrosis. Here we investigated the role of hypertension in NASH by comp...

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Detalles Bibliográficos
Autores principales: Yuan, Yuan, Naito, Hisao, Kitamori, Kazuya, Hashimoto, Sayuki, Asano, Tomomi, Nakajima, Tamie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735612/
https://www.ncbi.nlm.nih.gov/pubmed/33315911
http://dx.doi.org/10.1371/journal.pone.0243846

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