Real-Time Quantitative In-Cell NMR: Ligand Binding and Protein Oxidation Monitored in Human Cells Using Multivariate Curve Resolution

[Image: see text] In-cell NMR can investigate protein conformational changes at atomic resolution, such as those changes induced by drug binding or chemical modifications, directly in living human cells, and therefore has great potential in the context of drug development as it can provide an early...

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Detalles Bibliográficos
Autores principales: Luchinat, Enrico, Barbieri, Letizia, Campbell, Timothy F., Banci, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735651/
https://www.ncbi.nlm.nih.gov/pubmed/32551584
http://dx.doi.org/10.1021/acs.analchem.0c01677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735651/
https://www.ncbi.nlm.nih.gov/pubmed/32551584
http://dx.doi.org/10.1021/acs.analchem.0c01677

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