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Polyamines Mediate Folding of Primordial Hyperacidic Helical Proteins

[Image: see text] Polyamines are known to mediate diverse biological processes, and specifically to bind and stabilize compact conformations of nucleic acids, acting as chemical chaperones that promote folding by offsetting the repulsive negative charges of the phosphodiester backbone. However, whet...

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Detalles Bibliográficos
Autores principales: Despotović, Dragana, Longo, Liam M., Aharon, Einav, Kahana, Amit, Scherf, Tali, Gruic-Sovulj, Ita, Tawfik, Dan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735664/
https://www.ncbi.nlm.nih.gov/pubmed/33175508
http://dx.doi.org/10.1021/acs.biochem.0c00800