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Polyamines Mediate Folding of Primordial Hyperacidic Helical Proteins
[Image: see text] Polyamines are known to mediate diverse biological processes, and specifically to bind and stabilize compact conformations of nucleic acids, acting as chemical chaperones that promote folding by offsetting the repulsive negative charges of the phosphodiester backbone. However, whet...
Autores principales: | Despotović, Dragana, Longo, Liam M., Aharon, Einav, Kahana, Amit, Scherf, Tali, Gruic-Sovulj, Ita, Tawfik, Dan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735664/ https://www.ncbi.nlm.nih.gov/pubmed/33175508 http://dx.doi.org/10.1021/acs.biochem.0c00800 |
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