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Drug2ways: Reasoning over causal paths in biological networks for drug discovery

Elucidating the causal mechanisms responsible for disease can reveal potential therapeutic targets for pharmacological intervention and, accordingly, guide drug repositioning and discovery. In essence, the topology of a network can reveal the impact a drug candidate may have on a given biological st...

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Detalles Bibliográficos
Autores principales: Rivas-Barragan, Daniel, Mubeen, Sarah, Guim Bernat, Francesc, Hofmann-Apitius, Martin, Domingo-Fernández, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735677/
https://www.ncbi.nlm.nih.gov/pubmed/33264280
http://dx.doi.org/10.1371/journal.pcbi.1008464