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Drug2ways: Reasoning over causal paths in biological networks for drug discovery
Elucidating the causal mechanisms responsible for disease can reveal potential therapeutic targets for pharmacological intervention and, accordingly, guide drug repositioning and discovery. In essence, the topology of a network can reveal the impact a drug candidate may have on a given biological st...
Autores principales: | Rivas-Barragan, Daniel, Mubeen, Sarah, Guim Bernat, Francesc, Hofmann-Apitius, Martin, Domingo-Fernández, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735677/ https://www.ncbi.nlm.nih.gov/pubmed/33264280 http://dx.doi.org/10.1371/journal.pcbi.1008464 |
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