Controlled Diffusion of Photoswitchable Receptors by Binding Anti-electrostatic Hydrogen-Bonded Phosphate Oligomers

[Image: see text] Dihydrogen phosphate anions are found to spontaneously associate into anti-electrostatic oligomers via hydrogen bonding interactions at millimolar concentrations in DMSO. Diffusion NMR measurements supported formation of these oligomers, which can be bound by photoswitchable anion...

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Autores principales: MacDonald, Thomas S. C., Feringa, Ben L., Price, William S., Wezenberg, Sander J., Beves, Jonathon E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735709/
https://www.ncbi.nlm.nih.gov/pubmed/33180496
http://dx.doi.org/10.1021/jacs.0c09072
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author MacDonald, Thomas S. C.
Feringa, Ben L.
Price, William S.
Wezenberg, Sander J.
Beves, Jonathon E.
author_facet MacDonald, Thomas S. C.
Feringa, Ben L.
Price, William S.
Wezenberg, Sander J.
Beves, Jonathon E.
author_sort MacDonald, Thomas S. C.
collection PubMed
description [Image: see text] Dihydrogen phosphate anions are found to spontaneously associate into anti-electrostatic oligomers via hydrogen bonding interactions at millimolar concentrations in DMSO. Diffusion NMR measurements supported formation of these oligomers, which can be bound by photoswitchable anion receptors to form large bridged assemblies of approximately three times the volume of the unbound receptor. Photoisomerization of the oligomer-bound receptor causes a decrease in diffusion coefficient of up to 16%, corresponding to a 70% increase in effective volume. This new approach to external control of diffusion opens prospects in controlling molecular transport using light.
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spelling pubmed-77357092020-12-15 Controlled Diffusion of Photoswitchable Receptors by Binding Anti-electrostatic Hydrogen-Bonded Phosphate Oligomers MacDonald, Thomas S. C. Feringa, Ben L. Price, William S. Wezenberg, Sander J. Beves, Jonathon E. J Am Chem Soc [Image: see text] Dihydrogen phosphate anions are found to spontaneously associate into anti-electrostatic oligomers via hydrogen bonding interactions at millimolar concentrations in DMSO. Diffusion NMR measurements supported formation of these oligomers, which can be bound by photoswitchable anion receptors to form large bridged assemblies of approximately three times the volume of the unbound receptor. Photoisomerization of the oligomer-bound receptor causes a decrease in diffusion coefficient of up to 16%, corresponding to a 70% increase in effective volume. This new approach to external control of diffusion opens prospects in controlling molecular transport using light. American Chemical Society 2020-11-12 2020-11-25 /pmc/articles/PMC7735709/ /pubmed/33180496 http://dx.doi.org/10.1021/jacs.0c09072 Text en © 2020 American Chemical Society This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) , which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes.
spellingShingle MacDonald, Thomas S. C.
Feringa, Ben L.
Price, William S.
Wezenberg, Sander J.
Beves, Jonathon E.
Controlled Diffusion of Photoswitchable Receptors by Binding Anti-electrostatic Hydrogen-Bonded Phosphate Oligomers
title Controlled Diffusion of Photoswitchable Receptors by Binding Anti-electrostatic Hydrogen-Bonded Phosphate Oligomers
title_full Controlled Diffusion of Photoswitchable Receptors by Binding Anti-electrostatic Hydrogen-Bonded Phosphate Oligomers
title_fullStr Controlled Diffusion of Photoswitchable Receptors by Binding Anti-electrostatic Hydrogen-Bonded Phosphate Oligomers
title_full_unstemmed Controlled Diffusion of Photoswitchable Receptors by Binding Anti-electrostatic Hydrogen-Bonded Phosphate Oligomers
title_short Controlled Diffusion of Photoswitchable Receptors by Binding Anti-electrostatic Hydrogen-Bonded Phosphate Oligomers
title_sort controlled diffusion of photoswitchable receptors by binding anti-electrostatic hydrogen-bonded phosphate oligomers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735709/
https://www.ncbi.nlm.nih.gov/pubmed/33180496
http://dx.doi.org/10.1021/jacs.0c09072
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