Dissecting the DNA binding landscape and gene regulatory network of p63 and p53

The transcription factor p53 is the best-known tumor suppressor, but its sibling p63 is a master regulator of epidermis development and a key oncogenic driver in squamous cell carcinomas (SCC). Despite multiple gene expression studies becoming available, the limited overlap of reported p63-dependent...

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Detalles Bibliográficos
Autores principales: Riege, Konstantin, Kretzmer, Helene, Sahm, Arne, McDade, Simon S, Hoffmann, Steve, Fischer, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735755/
https://www.ncbi.nlm.nih.gov/pubmed/33263276
http://dx.doi.org/10.7554/eLife.63266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735755/
https://www.ncbi.nlm.nih.gov/pubmed/33263276
http://dx.doi.org/10.7554/eLife.63266

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