High-density transposon libraries utilising outward-oriented promoters identify mechanisms of action and resistance to antimicrobials

The use of bacterial transposon mutant libraries in phenotypic screens is a well-established technique for determining which genes are essential or advantageous for growth in conditions of interest. Standard, inactivating, transposon libraries cannot give direct information about genes whose over-ex...

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Detalles Bibliográficos
Autores principales: Coward, Chris, Dharmalingham, Gopujara, Abdulle, Omar, Avis, Tim, Beisken, Stephan, Breidenstein, Elena, Carli, Natasha, Figueiredo, Luis, Jones, David, Khan, Nawaz, Malara, Sara, Martins, Joana, Nagalingam, Nabeetha, Turner, Keith, Wain, John, Williams, David, Powell, David, Mason, Clive
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735965/
https://www.ncbi.nlm.nih.gov/pubmed/33186989
http://dx.doi.org/10.1093/femsle/fnaa185

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