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Investigation the effect of jujube seed capsule on sleep quality of postmenopausal women: A double-blind randomized clinical trial

BAKGROUND AND OBJECTIVE: Sleep disorder is among the most common problems in the life of postmenopausal women. Because of the complications of chemical drugs, many women prefer to use herbal supplements for relieving sleep problems. So, the main objective of this study was to determine the effect of...

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Autores principales: Mahmoudi, Razieh, Ansari, Somayeh, Haghighizadeh, Mohammad Hosein, Maram, Nader Shakiba, Montazeri, Simin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: China Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735973/
https://www.ncbi.nlm.nih.gov/pubmed/33854934
http://dx.doi.org/10.37796/2211-8039.1038
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author Mahmoudi, Razieh
Ansari, Somayeh
Haghighizadeh, Mohammad Hosein
Maram, Nader Shakiba
Montazeri, Simin
author_facet Mahmoudi, Razieh
Ansari, Somayeh
Haghighizadeh, Mohammad Hosein
Maram, Nader Shakiba
Montazeri, Simin
author_sort Mahmoudi, Razieh
collection PubMed
description BAKGROUND AND OBJECTIVE: Sleep disorder is among the most common problems in the life of postmenopausal women. Because of the complications of chemical drugs, many women prefer to use herbal supplements for relieving sleep problems. So, the main objective of this study was to determine the effect of the jujube seed capsule on sleep quality in postmenopausal women. MATERIALS AND METHODS: This study was a double-blind clinical trial conducted on 106 postmenopausal women in Khuzestan province, southwest of Iran. All participants were selected by a simple non-probability sampling method. Data were collected through a demographic data form and the Pittsburgh sleeps quality index (PSQI). Individuals were randomly divided into intervention (n = 53) and control (n = 53) groups. The intervention group received 250 mg oral jujube seed capsule and the control group received a placebo capsule twice a day for 21 days. After the treatment, the PSQI was completed in both intervention and control groups. Data were analyzed using the independent t-test and the Chi-square test using SPSS software version 24, and p-value < 0.05 was considered as the significance level. RESULTS: The results revealed that after treatment, the mean scores of sleep quality decreased in the intervention and control group. Although this difference was statistically significant in both intervention and control groups (p-value < 0.05), more reduction observed in the intervention group (p-value < 0.001). CONCLUSION: Consumption of the jujube seed capsule had a positive impact on improving the sleep quality of postmenopausal women and could be recommended as a useful herbal medication.
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spelling pubmed-77359732020-12-15 Investigation the effect of jujube seed capsule on sleep quality of postmenopausal women: A double-blind randomized clinical trial Mahmoudi, Razieh Ansari, Somayeh Haghighizadeh, Mohammad Hosein Maram, Nader Shakiba Montazeri, Simin Biomedicine (Taipei) Original Article BAKGROUND AND OBJECTIVE: Sleep disorder is among the most common problems in the life of postmenopausal women. Because of the complications of chemical drugs, many women prefer to use herbal supplements for relieving sleep problems. So, the main objective of this study was to determine the effect of the jujube seed capsule on sleep quality in postmenopausal women. MATERIALS AND METHODS: This study was a double-blind clinical trial conducted on 106 postmenopausal women in Khuzestan province, southwest of Iran. All participants were selected by a simple non-probability sampling method. Data were collected through a demographic data form and the Pittsburgh sleeps quality index (PSQI). Individuals were randomly divided into intervention (n = 53) and control (n = 53) groups. The intervention group received 250 mg oral jujube seed capsule and the control group received a placebo capsule twice a day for 21 days. After the treatment, the PSQI was completed in both intervention and control groups. Data were analyzed using the independent t-test and the Chi-square test using SPSS software version 24, and p-value < 0.05 was considered as the significance level. RESULTS: The results revealed that after treatment, the mean scores of sleep quality decreased in the intervention and control group. Although this difference was statistically significant in both intervention and control groups (p-value < 0.05), more reduction observed in the intervention group (p-value < 0.001). CONCLUSION: Consumption of the jujube seed capsule had a positive impact on improving the sleep quality of postmenopausal women and could be recommended as a useful herbal medication. China Medical University 2020-12-01 /pmc/articles/PMC7735973/ /pubmed/33854934 http://dx.doi.org/10.37796/2211-8039.1038 Text en © the Author(s) This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Article
Mahmoudi, Razieh
Ansari, Somayeh
Haghighizadeh, Mohammad Hosein
Maram, Nader Shakiba
Montazeri, Simin
Investigation the effect of jujube seed capsule on sleep quality of postmenopausal women: A double-blind randomized clinical trial
title Investigation the effect of jujube seed capsule on sleep quality of postmenopausal women: A double-blind randomized clinical trial
title_full Investigation the effect of jujube seed capsule on sleep quality of postmenopausal women: A double-blind randomized clinical trial
title_fullStr Investigation the effect of jujube seed capsule on sleep quality of postmenopausal women: A double-blind randomized clinical trial
title_full_unstemmed Investigation the effect of jujube seed capsule on sleep quality of postmenopausal women: A double-blind randomized clinical trial
title_short Investigation the effect of jujube seed capsule on sleep quality of postmenopausal women: A double-blind randomized clinical trial
title_sort investigation the effect of jujube seed capsule on sleep quality of postmenopausal women: a double-blind randomized clinical trial
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7735973/
https://www.ncbi.nlm.nih.gov/pubmed/33854934
http://dx.doi.org/10.37796/2211-8039.1038
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