Osteoporosis in Inflammatory Arthritides: New Perspective on Pathogenesis and Treatment

Osteoporosis is a skeletal disorder characterized by impaired bone strength and increased risk of fragility fracture and is among the most relevant comorbidities of rheumatic diseases. The purpose of the present review is to discuss the pathogenesis of local and systemic bone involvement in inflamma...

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Autores principales: Rotta, Denise, Fassio, Angelo, Rossini, Maurizio, Giollo, Alessandro, Viapiana, Ombretta, Orsolini, Giovanni, Bertoldo, Eugenia, Gatti, Davide, Adami, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736072/
https://www.ncbi.nlm.nih.gov/pubmed/33335907
http://dx.doi.org/10.3389/fmed.2020.613720
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author Rotta, Denise
Fassio, Angelo
Rossini, Maurizio
Giollo, Alessandro
Viapiana, Ombretta
Orsolini, Giovanni
Bertoldo, Eugenia
Gatti, Davide
Adami, Giovanni
author_facet Rotta, Denise
Fassio, Angelo
Rossini, Maurizio
Giollo, Alessandro
Viapiana, Ombretta
Orsolini, Giovanni
Bertoldo, Eugenia
Gatti, Davide
Adami, Giovanni
author_sort Rotta, Denise
collection PubMed
description Osteoporosis is a skeletal disorder characterized by impaired bone strength and increased risk of fragility fracture and is among the most relevant comorbidities of rheumatic diseases. The purpose of the present review is to discuss the pathogenesis of local and systemic bone involvement in inflammatory arthritides, especially Rheumatoid Arthritis, Psoriatic Arthritis, and Spondyloarthritides, as well as the effect of anti-rheumatic treatments and anti-osteoporotic medication on bone health and fracture incidence, including recent data on novel therapeutic perspective.
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spelling pubmed-77360722020-12-16 Osteoporosis in Inflammatory Arthritides: New Perspective on Pathogenesis and Treatment Rotta, Denise Fassio, Angelo Rossini, Maurizio Giollo, Alessandro Viapiana, Ombretta Orsolini, Giovanni Bertoldo, Eugenia Gatti, Davide Adami, Giovanni Front Med (Lausanne) Medicine Osteoporosis is a skeletal disorder characterized by impaired bone strength and increased risk of fragility fracture and is among the most relevant comorbidities of rheumatic diseases. The purpose of the present review is to discuss the pathogenesis of local and systemic bone involvement in inflammatory arthritides, especially Rheumatoid Arthritis, Psoriatic Arthritis, and Spondyloarthritides, as well as the effect of anti-rheumatic treatments and anti-osteoporotic medication on bone health and fracture incidence, including recent data on novel therapeutic perspective. Frontiers Media S.A. 2020-12-01 /pmc/articles/PMC7736072/ /pubmed/33335907 http://dx.doi.org/10.3389/fmed.2020.613720 Text en Copyright © 2020 Rotta, Fassio, Rossini, Giollo, Viapiana, Orsolini, Bertoldo, Gatti and Adami. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Rotta, Denise
Fassio, Angelo
Rossini, Maurizio
Giollo, Alessandro
Viapiana, Ombretta
Orsolini, Giovanni
Bertoldo, Eugenia
Gatti, Davide
Adami, Giovanni
Osteoporosis in Inflammatory Arthritides: New Perspective on Pathogenesis and Treatment
title Osteoporosis in Inflammatory Arthritides: New Perspective on Pathogenesis and Treatment
title_full Osteoporosis in Inflammatory Arthritides: New Perspective on Pathogenesis and Treatment
title_fullStr Osteoporosis in Inflammatory Arthritides: New Perspective on Pathogenesis and Treatment
title_full_unstemmed Osteoporosis in Inflammatory Arthritides: New Perspective on Pathogenesis and Treatment
title_short Osteoporosis in Inflammatory Arthritides: New Perspective on Pathogenesis and Treatment
title_sort osteoporosis in inflammatory arthritides: new perspective on pathogenesis and treatment
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736072/
https://www.ncbi.nlm.nih.gov/pubmed/33335907
http://dx.doi.org/10.3389/fmed.2020.613720
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