Cargando…

Copper-64 Chloride Exhibits Therapeutic Potential in Three-Dimensional Cellular Models of Prostate Cancer

Prostate cancer (PCa) is the second most common cancer type in men, and in advanced metastatic stages is considerable incurable. This justifies the need for efficient early diagnostic methods and novel therapies, particularly radiopharmaceuticals with the potential for simultaneous diagnosis and the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pinto, Catarina I. G., Bucar, Sara, Alves, Vítor, Fonseca, Alexandra, Abrunhosa, Antero J., da Silva, Cláudia L., Guerreiro, Joana F., Mendes, Filipa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736412/ https://www.ncbi.nlm.nih.gov/pubmed/33335914 http://dx.doi.org/10.3389/fmolb.2020.609172

Ejemplares similares

Radiobiological Characterization of (64)CuCl(2) as a Simple Tool for Prostate Cancer Theranostics
por: Guerreiro, Joana Fernandes, et al.
Publicado: (2018)

Antibody and Nanobody Radiolabeling with Copper-64: Solid vs. Liquid Target Approach
por: Hrynchak, Ivanna, et al.
Publicado: (2023)

Molecular Architecture of the Antiophidic Protein DM64 and its Binding Specificity to Myotoxin II From Bothrops asper Venom
por: Soares, Barbara S., et al.
Publicado: (2022)

Editorial: Unravelling Copper-Regulatory Systems and Copper-Affected Pathways in Cancer Cells to Improve Current Therapies
por: Chen, Xin, et al.
Publicado: (2022)

Role of Copper on Mitochondrial Function and Metabolism
por: Ruiz, Lina M., et al.
Publicado: (2021)

Selective Targeting of Cancer Cells by Copper Ionophores: An Overview
por: Oliveri, Valentina
Publicado: (2022)

Targeting Ubiquitin–Proteasome System With Copper Complexes for Cancer Therapy
por: Chen, Xin, et al.
Publicado: (2021)

Copper Modulates the Catalytic Activity of Protein Kinase CK2
por: Chojnowski, John E., et al.
Publicado: (2022)

Less is more: Enterobactin concentration dependency in copper tolerance and toxicity
por: Peralta, Daiana Romina, et al.
Publicado: (2022)

Long-Lived Species of Bivalves Exhibit Low MT-DNA Substitution Rates
por: Mortz, Mathieu, et al.
Publicado: (2021)

TRAIL-R1-Targeted CAR-T Cells Exhibit Dual Antitumor Efficacy
por: Nai, Yaru, et al.
Publicado: (2021)

Copper regulation of immune response and potential implications for treating orthopedic disorders
por: Liu, Yamei, et al.
Publicado: (2022)

Recent Advances in Repurposing Disulfiram and Disulfiram Derivatives as Copper-Dependent Anticancer Agents
por: Kannappan, Vinodh, et al.
Publicado: (2021)

Fatty Acid Uptake in Liver Hepatocytes Induces Relocalization and Sequestration of Intracellular Copper
por: Harder, Nathaniel H. O., et al.
Publicado: (2022)

The Copper Efflux Regulator CueR Is Subject to ATP-Dependent Proteolysis in Escherichia coli
por: Bittner, Lisa-Marie, et al.
Publicado: (2017)

Biochemical and Structural Characterization of Thermostable GH159 Glycoside Hydrolases Exhibiting α-L-Arabinofuranosidase Activity
por: Baudrexl, Melanie, et al.
Publicado: (2022)

Using Dimensionality Reduction to Analyze Protein Trajectories
por: Tribello, Gareth A., et al.
Publicado: (2019)

Two-dimensional measurements of receptor-ligand interactions
por: Zheng, Songjie, et al.
Publicado: (2023)

The copper transporter CTR1 and cisplatin accumulation at the single-cell level by LA-ICP-TOFMS
por: Schoeberl, Anna, et al.
Publicado: (2022)

Missense Mutations Modify the Conformational Ensemble of the α-Synuclein Monomer Which Exhibits a Two-Phase Characteristic
por: Guzzo, Adrien, et al.
Publicado: (2021)

Glycan-related genes in human gut microbiota exhibit differential distribution and diversity in carbohydrate degradation and glycan synthesis
por: Takihara, Hayato, et al.
Publicado: (2023)

Structural Insights Into the Effects of Interactions With Iron and Copper Ions on Ferritin From the Blood Clam Tegillarca granosa
por: Ming, Tinghong, et al.
Publicado: (2022)

Hippophae rhamnoides L. (sea buckthorn) mediated green synthesis of copper nanoparticles and their application in anticancer activity
por: Dadhwal, Pooja, et al.
Publicado: (2023)

Crystalline Sponge Method by Three-Dimensional Electron Diffraction
por: Chen, Pohua, et al.
Publicado: (2022)

Optimal Experimental Design Based on Two-Dimensional Likelihood Profiles
por: Litwin, Tim, et al.
Publicado: (2022)

Supported Lipid Bilayers and the Study of Two-Dimensional Binding Kinetics
por: Dam, Tommy, et al.
Publicado: (2022)

Sonochemical synthesis of a copper reduced graphene oxide nanocomposite using honey and evaluation of its antibacterial and cytotoxic activities
por: Ismail, Nur Afini, et al.
Publicado: (2022)

Production of GMP-Compliant Clinical Amounts of Copper-61 Radiopharmaceuticals from Liquid Targets
por: Fonseca, Alexandra I., et al.
Publicado: (2022)

The Sequence and Three-Dimensional Structure Characterization of Snake Venom Phospholipases B
por: Ullah, Anwar, et al.
Publicado: (2020)

Selection of Effective Therapies Using Three-Dimensional in vitro Modeling of Chondrosarcoma
por: Palubeckaitė, Ieva, et al.
Publicado: (2020)

Metabolic profiling of induced acute pancreatitis and pancreatic cancer progression in a mutant Kras mouse model
por: Carneiro, Tatiana J., et al.
Publicado: (2022)

Heterogeneous nuclear ribonucleoprotein hnRNPA2/B1 regulates the abundance of the copper-transporter ATP7A in an isoform-dependent manner
por: McCann, Courtney J., et al.
Publicado: (2022)

The XBB.1.5 slightly increase the binding affinity for host receptor ACE2 and exhibit strongest immune escaping features: molecular modeling and free energy calculation
por: Suleman, Muhammad, et al.
Publicado: (2023)

Multinuclear Metal-Binding Ability of the N-Terminal Region of Human Copper Transporter Ctr1: Dependence Upon pH and Metal Oxidation State
por: Nardella, Maria Incoronata, et al.
Publicado: (2022)

Multi-Dimensional Display of Wang’s Lymph Node Map Using Virtual Bronchoscopic Navigation System
por: Lan, Fen, et al.
Publicado: (2021)

A Three-Dimensional Organoid Model of Primary Breast Cancer to Investigate the Effects of Oncolytic Virotherapy
por: Carter, Mary E., et al.
Publicado: (2022)

Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design
por: Thomas, Sherine E., et al.
Publicado: (2022)

Reconstruction of Three-Dimensional Conformations of Bacterial ClpB from High-Speed Atomic-Force-Microscopy Images
por: Dasgupta, Bhaskar, et al.
Publicado: (2021)

Proteomic Identification of a Gastric Tumor ECM Signature Associated With Cancer Progression
por: Moreira, Ana M., et al.
Publicado: (2022)

Why Selenocysteine Is Unique?
por: Serrão, Vitor Hugo Balasco, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_oi264ut8gro0b09hfpvcidanif