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Logistic regression analysis of environmental and other variables and incidences of tuberculosis in respiratory patients

The objective of this study was to examine the association of 14 variables with TB in respiratory patients. The variables included: urban/rural, persons in 1200 sqft area, TB in family, crowding, smoking (family member), gender, age, education, smoking, workplace, kitchen location, cooking fuel, ven...

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Detalles Bibliográficos
Autores principales: Pathak, Ashutosh K., Sharma, Mukesh, Katiyar, Subodh K., Katiyar, Sandeep, Nagar, Pavan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736574/
https://www.ncbi.nlm.nih.gov/pubmed/33318598
http://dx.doi.org/10.1038/s41598-020-79023-5
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author Pathak, Ashutosh K.
Sharma, Mukesh
Katiyar, Subodh K.
Katiyar, Sandeep
Nagar, Pavan K.
author_facet Pathak, Ashutosh K.
Sharma, Mukesh
Katiyar, Subodh K.
Katiyar, Sandeep
Nagar, Pavan K.
author_sort Pathak, Ashutosh K.
collection PubMed
description The objective of this study was to examine the association of 14 variables with TB in respiratory patients. The variables included: urban/rural, persons in 1200 sqft area, TB in family, crowding, smoking (family member), gender, age, education, smoking, workplace, kitchen location, cooking fuel, ventilation, and kerosene uses. Eight hundred respiratory patients were tested for sputum positive pulmonary TB; 500 had TB and 300 did not. An analysis of the unadjusted odds ratio (UOR) and adjusted OR (AOR) was undertaken using logistic regression to link the probability of TB incidences with the variables. There was an inconsistency in the significance of variables using UOR and AOR. A subset model of 4 variables (kerosene uses, ventilation, workplace, and gender) based on significant AOR was adjudged acceptable for estimating the probability of TB incidences. Uses of kerosene (AOR 2.62 (1.95, 3.54)) consistently related to incidences of TB. It was estimated that 50% reduction in kerosene uses could reduce the probability of TB by 13.29% in respiratory patients. The major recommendation was to replace kerosene uses from households with a supply of clean fuel like liquid petroleum or natural gas and rural electrification.
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spelling pubmed-77365742020-12-15 Logistic regression analysis of environmental and other variables and incidences of tuberculosis in respiratory patients Pathak, Ashutosh K. Sharma, Mukesh Katiyar, Subodh K. Katiyar, Sandeep Nagar, Pavan K. Sci Rep Article The objective of this study was to examine the association of 14 variables with TB in respiratory patients. The variables included: urban/rural, persons in 1200 sqft area, TB in family, crowding, smoking (family member), gender, age, education, smoking, workplace, kitchen location, cooking fuel, ventilation, and kerosene uses. Eight hundred respiratory patients were tested for sputum positive pulmonary TB; 500 had TB and 300 did not. An analysis of the unadjusted odds ratio (UOR) and adjusted OR (AOR) was undertaken using logistic regression to link the probability of TB incidences with the variables. There was an inconsistency in the significance of variables using UOR and AOR. A subset model of 4 variables (kerosene uses, ventilation, workplace, and gender) based on significant AOR was adjudged acceptable for estimating the probability of TB incidences. Uses of kerosene (AOR 2.62 (1.95, 3.54)) consistently related to incidences of TB. It was estimated that 50% reduction in kerosene uses could reduce the probability of TB by 13.29% in respiratory patients. The major recommendation was to replace kerosene uses from households with a supply of clean fuel like liquid petroleum or natural gas and rural electrification. Nature Publishing Group UK 2020-12-14 /pmc/articles/PMC7736574/ /pubmed/33318598 http://dx.doi.org/10.1038/s41598-020-79023-5 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Pathak, Ashutosh K.
Sharma, Mukesh
Katiyar, Subodh K.
Katiyar, Sandeep
Nagar, Pavan K.
Logistic regression analysis of environmental and other variables and incidences of tuberculosis in respiratory patients
title Logistic regression analysis of environmental and other variables and incidences of tuberculosis in respiratory patients
title_full Logistic regression analysis of environmental and other variables and incidences of tuberculosis in respiratory patients
title_fullStr Logistic regression analysis of environmental and other variables and incidences of tuberculosis in respiratory patients
title_full_unstemmed Logistic regression analysis of environmental and other variables and incidences of tuberculosis in respiratory patients
title_short Logistic regression analysis of environmental and other variables and incidences of tuberculosis in respiratory patients
title_sort logistic regression analysis of environmental and other variables and incidences of tuberculosis in respiratory patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736574/
https://www.ncbi.nlm.nih.gov/pubmed/33318598
http://dx.doi.org/10.1038/s41598-020-79023-5
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