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Combined PI3Kα-mTOR Targeting of Glioma Stem Cells

Glioblastoma (GBM) is the most common and lethal primary intrinsic tumour of the adult brain and evidence indicates disease progression is driven by glioma stem cells (GSCs). Extensive advances in the molecular characterization of GBM allowed classification into proneural, mesenchymal and classical...

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Detalles Bibliográficos
Autores principales: Eckerdt, Frank D., Bell, Jonathan B., Gonzalez, Christopher, Oh, Michael S., Perez, Ricardo E., Mazewski, Candice, Fischietti, Mariafausta, Goldman, Stewart, Nakano, Ichiro, Platanias, Leonidas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736588/
https://www.ncbi.nlm.nih.gov/pubmed/33318517
http://dx.doi.org/10.1038/s41598-020-78788-z

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