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Senescent Cell Depletion Through Targeting BCL-Family Proteins and Mitochondria
Senescent cells with replicative arrest can be generated during genotoxic, oxidative, and oncogenic stress. Long-term retention of senescent cells in the body, which is attributed to highly expressed BCL-family proteins, chronically damages tissues mainly through a senescence-associated secretory ph...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736607/ https://www.ncbi.nlm.nih.gov/pubmed/33335487 http://dx.doi.org/10.3389/fphys.2020.593630 |