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Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis
Introduction: With the development of antibody detection technology, Gamma-Aminobutyric Acid (GABA) B receptor encephalitis is a known autoimmune disease. This paper describes a patient with refractory hypotension who suffered GABA B receptor autoimmune encephalitis. Case Report: We describe a 63-ye...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736632/ https://www.ncbi.nlm.nih.gov/pubmed/33335508 http://dx.doi.org/10.3389/fneur.2020.571382 |
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author | Hanxin, Kong Xiaomin, Wang Hao, Ying Shuihong, Zheng |
author_facet | Hanxin, Kong Xiaomin, Wang Hao, Ying Shuihong, Zheng |
author_sort | Hanxin, Kong |
collection | PubMed |
description | Introduction: With the development of antibody detection technology, Gamma-Aminobutyric Acid (GABA) B receptor encephalitis is a known autoimmune disease. This paper describes a patient with refractory hypotension who suffered GABA B receptor autoimmune encephalitis. Case Report: We describe a 63-year-old man with GABA B receptor autoimmune encephalitis who had hypotension on day 17 of the disease onset. Despite two rounds of immunoglobulin administration, high-dose intravenous steroid injections and immunosuppressive therapy on day 35 of hospitalization, psychiatric symptoms and seizures were significantly improved; however, the patient's blood pressure remained low. Conclusion: This case study and literature review investigated the impairment of autonomic nerve function and its subsequent management in patients with GABA B receptor autoimmune encephalitis. |
format | Online Article Text |
id | pubmed-7736632 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77366322020-12-16 Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis Hanxin, Kong Xiaomin, Wang Hao, Ying Shuihong, Zheng Front Neurol Neurology Introduction: With the development of antibody detection technology, Gamma-Aminobutyric Acid (GABA) B receptor encephalitis is a known autoimmune disease. This paper describes a patient with refractory hypotension who suffered GABA B receptor autoimmune encephalitis. Case Report: We describe a 63-year-old man with GABA B receptor autoimmune encephalitis who had hypotension on day 17 of the disease onset. Despite two rounds of immunoglobulin administration, high-dose intravenous steroid injections and immunosuppressive therapy on day 35 of hospitalization, psychiatric symptoms and seizures were significantly improved; however, the patient's blood pressure remained low. Conclusion: This case study and literature review investigated the impairment of autonomic nerve function and its subsequent management in patients with GABA B receptor autoimmune encephalitis. Frontiers Media S.A. 2020-12-01 /pmc/articles/PMC7736632/ /pubmed/33335508 http://dx.doi.org/10.3389/fneur.2020.571382 Text en Copyright © 2020 Hanxin, Xiaomin, Hao and Shuihong. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology Hanxin, Kong Xiaomin, Wang Hao, Ying Shuihong, Zheng Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis |
title | Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis |
title_full | Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis |
title_fullStr | Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis |
title_full_unstemmed | Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis |
title_short | Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis |
title_sort | case report: refractory hypotension of gaba b receptor autoimmune encephalitis |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736632/ https://www.ncbi.nlm.nih.gov/pubmed/33335508 http://dx.doi.org/10.3389/fneur.2020.571382 |
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