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Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis

Introduction: With the development of antibody detection technology, Gamma-Aminobutyric Acid (GABA) B receptor encephalitis is a known autoimmune disease. This paper describes a patient with refractory hypotension who suffered GABA B receptor autoimmune encephalitis. Case Report: We describe a 63-ye...

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Autores principales: Hanxin, Kong, Xiaomin, Wang, Hao, Ying, Shuihong, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736632/
https://www.ncbi.nlm.nih.gov/pubmed/33335508
http://dx.doi.org/10.3389/fneur.2020.571382
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author Hanxin, Kong
Xiaomin, Wang
Hao, Ying
Shuihong, Zheng
author_facet Hanxin, Kong
Xiaomin, Wang
Hao, Ying
Shuihong, Zheng
author_sort Hanxin, Kong
collection PubMed
description Introduction: With the development of antibody detection technology, Gamma-Aminobutyric Acid (GABA) B receptor encephalitis is a known autoimmune disease. This paper describes a patient with refractory hypotension who suffered GABA B receptor autoimmune encephalitis. Case Report: We describe a 63-year-old man with GABA B receptor autoimmune encephalitis who had hypotension on day 17 of the disease onset. Despite two rounds of immunoglobulin administration, high-dose intravenous steroid injections and immunosuppressive therapy on day 35 of hospitalization, psychiatric symptoms and seizures were significantly improved; however, the patient's blood pressure remained low. Conclusion: This case study and literature review investigated the impairment of autonomic nerve function and its subsequent management in patients with GABA B receptor autoimmune encephalitis.
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spelling pubmed-77366322020-12-16 Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis Hanxin, Kong Xiaomin, Wang Hao, Ying Shuihong, Zheng Front Neurol Neurology Introduction: With the development of antibody detection technology, Gamma-Aminobutyric Acid (GABA) B receptor encephalitis is a known autoimmune disease. This paper describes a patient with refractory hypotension who suffered GABA B receptor autoimmune encephalitis. Case Report: We describe a 63-year-old man with GABA B receptor autoimmune encephalitis who had hypotension on day 17 of the disease onset. Despite two rounds of immunoglobulin administration, high-dose intravenous steroid injections and immunosuppressive therapy on day 35 of hospitalization, psychiatric symptoms and seizures were significantly improved; however, the patient's blood pressure remained low. Conclusion: This case study and literature review investigated the impairment of autonomic nerve function and its subsequent management in patients with GABA B receptor autoimmune encephalitis. Frontiers Media S.A. 2020-12-01 /pmc/articles/PMC7736632/ /pubmed/33335508 http://dx.doi.org/10.3389/fneur.2020.571382 Text en Copyright © 2020 Hanxin, Xiaomin, Hao and Shuihong. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Hanxin, Kong
Xiaomin, Wang
Hao, Ying
Shuihong, Zheng
Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis
title Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis
title_full Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis
title_fullStr Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis
title_full_unstemmed Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis
title_short Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis
title_sort case report: refractory hypotension of gaba b receptor autoimmune encephalitis
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736632/
https://www.ncbi.nlm.nih.gov/pubmed/33335508
http://dx.doi.org/10.3389/fneur.2020.571382
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