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Geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone

PURPOSE: Age in severely injured patients has been increasing for decades. Older age is associated with increasing mortality. However, morbidity and mortality could possibly be reduced when accurate and aggressive treatment is provided. This study investigated age-related morbidity and mortality in...

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Autores principales: van Wessem, Karlijn J. P., Leenen, Luke P. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736672/
https://www.ncbi.nlm.nih.gov/pubmed/33320284
http://dx.doi.org/10.1007/s00068-020-01567-y
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author van Wessem, Karlijn J. P.
Leenen, Luke P. H.
author_facet van Wessem, Karlijn J. P.
Leenen, Luke P. H.
author_sort van Wessem, Karlijn J. P.
collection PubMed
description PURPOSE: Age in severely injured patients has been increasing for decades. Older age is associated with increasing mortality. However, morbidity and mortality could possibly be reduced when accurate and aggressive treatment is provided. This study investigated age-related morbidity and mortality in polytrauma including age-related decisions in initial injury management and withdrawal of life-sustaining therapy (WLST). METHODS: A 6.5-year prospective cohort study included consecutive severely injured trauma patients admitted to a Level-1 Trauma Center ICU. Demographics, data on physiology, resuscitation, MODS/ARDS, and infectious complications were prospectively collected. Patients were divided into age subgroups (< 25, 25–49, 50–69, and ≥ 70 years) to make clinically relevant comparisons. RESULTS: 391 patients (70% males) were included with median ISS of 29 (22–36), 95% sustained blunt injuries. There was no difference in injury severity, resuscitation, urgent surgeries, nor in ventilator days, ICU-LOS, and H-LOS between age groups. Adjusted odds of MODS, ARDS and infectious complications were similar between age groups. 47% of patients ≥ 70 years died, compared to 10–16% in other age groups (P < 0.001). WLST increased with older age, contributing to more than half of deaths ≥ 70 years. TBI was the most common cause of death and decision for treatment withdrawal in all age groups. CONCLUSIONS: Patients ≥ 70 years had higher mortality risk even though injury severity and complication rates were similar to other age groups. WLST increased with age with the vast majority due to brain injury. More than half of patients ≥ 70 years survived suggesting geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00068-020-01567-y.
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spelling pubmed-77366722020-12-15 Geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone van Wessem, Karlijn J. P. Leenen, Luke P. H. Eur J Trauma Emerg Surg Original Article PURPOSE: Age in severely injured patients has been increasing for decades. Older age is associated with increasing mortality. However, morbidity and mortality could possibly be reduced when accurate and aggressive treatment is provided. This study investigated age-related morbidity and mortality in polytrauma including age-related decisions in initial injury management and withdrawal of life-sustaining therapy (WLST). METHODS: A 6.5-year prospective cohort study included consecutive severely injured trauma patients admitted to a Level-1 Trauma Center ICU. Demographics, data on physiology, resuscitation, MODS/ARDS, and infectious complications were prospectively collected. Patients were divided into age subgroups (< 25, 25–49, 50–69, and ≥ 70 years) to make clinically relevant comparisons. RESULTS: 391 patients (70% males) were included with median ISS of 29 (22–36), 95% sustained blunt injuries. There was no difference in injury severity, resuscitation, urgent surgeries, nor in ventilator days, ICU-LOS, and H-LOS between age groups. Adjusted odds of MODS, ARDS and infectious complications were similar between age groups. 47% of patients ≥ 70 years died, compared to 10–16% in other age groups (P < 0.001). WLST increased with older age, contributing to more than half of deaths ≥ 70 years. TBI was the most common cause of death and decision for treatment withdrawal in all age groups. CONCLUSIONS: Patients ≥ 70 years had higher mortality risk even though injury severity and complication rates were similar to other age groups. WLST increased with age with the vast majority due to brain injury. More than half of patients ≥ 70 years survived suggesting geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00068-020-01567-y. Springer Berlin Heidelberg 2020-12-15 2022 /pmc/articles/PMC7736672/ /pubmed/33320284 http://dx.doi.org/10.1007/s00068-020-01567-y Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
van Wessem, Karlijn J. P.
Leenen, Luke P. H.
Geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone
title Geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone
title_full Geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone
title_fullStr Geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone
title_full_unstemmed Geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone
title_short Geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone
title_sort geriatric polytrauma patients should not be excluded from aggressive injury treatment based on age alone
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736672/
https://www.ncbi.nlm.nih.gov/pubmed/33320284
http://dx.doi.org/10.1007/s00068-020-01567-y
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