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The TFIIH subunits p44/p62 act as a damage sensor during nucleotide excision repair

Nucleotide excision repair (NER) in eukaryotes is orchestrated by the core form of the general transcription factor TFIIH, containing the helicases XPB, XPD and five ‘structural’ subunits, p62, p44, p34, p52 and p8. Recent cryo-EM structures show that p62 makes extensive contacts with p44 and in par...

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Detalles Bibliográficos
Autores principales:	Barnett, Jamie T, Kuper, Jochen, Koelmel, Wolfgang, Kisker, Caroline, Kad, Neil M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736792/ https://www.ncbi.nlm.nih.gov/pubmed/33166411 http://dx.doi.org/10.1093/nar/gkaa973

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