BCCIP is required for nucleolar recruitment of eIF6 and 12S pre-rRNA production during 60S ribosome biogenesis

Ribosome biogenesis is a fundamental process required for cell proliferation. Although evolutionally conserved, the mammalian ribosome assembly system is more complex than in yeasts. BCCIP was originally identified as a BRCA2 and p21 interacting protein. A partial loss of BCCIP function was sufficie...

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Detalles Bibliográficos
Autores principales: Ye, Caiyong, Liu, Bochao, Lu, Huimei, Liu, Jingmei, Rabson, Arnold B, Jacinto, Estela, Pestov, Dimitri G, Shen, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736804/
https://www.ncbi.nlm.nih.gov/pubmed/33245766
http://dx.doi.org/10.1093/nar/gkaa1114

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