RedEx: a method for seamless DNA insertion and deletion in large multimodular polyketide synthase gene clusters

Biosynthesis reprograming is an important way to diversify chemical structures. The large repetitive DNA sequences existing in polyketide synthase genes make seamless DNA manipulation of the polyketide biosynthetic gene clusters extremely challenging. In this study, to replace the ethyl group attach...

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Detalles Bibliográficos
Autores principales: Song, Chaoyi, Luan, Ji, Li, Ruijuan, Jiang, Chanjuan, Hou, Yu, Cui, Qingwen, Cui, Tianqi, Tan, Long, Ma, Zaichao, Tang, Ya-Jie, Stewart, A Francis, Fu, Jun, Zhang, Youming, Wang, Hailong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7736807/
https://www.ncbi.nlm.nih.gov/pubmed/33119745
http://dx.doi.org/10.1093/nar/gkaa956

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